Azalomycin

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Names

[ CAS No. ]:
37318-06-2

[ Name ]:
Azalomycin

[Synonym ]:
(3E,5E,7S,8S,11E,13E,15S,16S)-8,16-Bis{(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-{[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-ethyl-2-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-7,15-dimethyl-1,9-dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione (non-preferred name)
(3E,5E,7S,8S,11E,13E,15S,16S)-8,16-Bis{(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-{[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-ethyl-2-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-hydroxy-2-pentanyl}-7,15-dimethyl-1,9-dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione
5001B
gopalamicin
Azalomycin
Azalomycin-B,Gopalamicin,SNA 4606-3
Antibiotic 56-62
Elaiofilin
Salbomycin
Elaiophylin,Salbomycin,Gopalamicin,SNA 4606-3,Azalomycin-B
(3E,5E,7S,8S,11E,13E,15S,16S)-8,16-bis[(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-ethyl-2-hydroxy-6-methyloxan-2-yl]-3-hydroxypentan-2-yl]-7,15-dimethyl-1,9-dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione
Antibiotic 5001B
azalomycin B
Elaiophylin

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1080.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C54H88O18

[ Molecular Weight ]:
1025.27

[ Flash Point ]:
295.8±27.8 °C

[ Exact Mass ]:
1024.597046

[ PSA ]:
269.82000

[ LogP ]:
2.59

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CL8380000
CHEMICAL NAME :
Azalomycin B
CAS REGISTRY NUMBER :
37318-06-2
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C54-H88-O13
MOLECULAR WEIGHT :
945.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
281 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 13,51,1960

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  •

DownStream

Related Compounds

  • Azalomycin
  • AZALOMYCIN M
  • azalomycin-F
  • azalomycin F4
  • Antibiotic K178,Antibiotic X464,Azalomycin M,Helexin C,Polyetherin A
  • 4-Ethenyl-3-nitrobenzaldehyde
  • 1-Chloro-N,2-dimethyl-1-propen-1-amine
  • 2-Acetamido-2,3,3-trimethylbutanoic acid
  • N-Methyl-1-(3-methyl-3-bicyclo[3.1.0]hexanyl)methanamine
  • 6-Iodo-3-methoxypicolinonitrile
  • 3-(3,3-Dimethylcyclopentyl)pyrrolidine
  • 3,4-Dichloro-1-[(3-fluorophenyl)methyl]-1H-pyrrole-2,5-dione
  • 2,4-Dichloro-6-[4-chloro-2-(1-phenylethyl)phenoxy]-1,3,5-triazine
  • Methyl 3-(azetidin-2-yl)propanoate
  • 1-(Azetidin-2-ylmethyl)piperidine
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