MYCOPHENOLATE SODIUM
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Names
[ CAS No. ]:
37415-62-6
[ Name ]:
MYCOPHENOLATE SODIUM
[Synonym ]:
mycophenolicmonosodiumsalt
MYCOPHENOLATE SODIUM
Mycophenolic acid monosodium salt
sodiummycophenolate
mycophenolicacidmonosodiumsalt
Chemical & Physical Properties
[ Density]:
1.29 g/cm3
[ Boiling Point ]:
611.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H20NaO6+
[ Molecular Weight ]:
343.32700
[ Flash Point ]:
225.8ºC
[ Exact Mass ]:
343.11600
[ PSA ]:
93.06000
[ LogP ]:
2.73320
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MP8100000
- CHEMICAL NAME :
- 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4 -methyl-, sodium salt
- CAS REGISTRY NUMBER :
- 37415-62-6
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C17-H19-O6.Na
- MOLECULAR WEIGHT :
- 342.35
- WISWESSER LINE NOTATION :
- T56 BVO DHJ FQ G2UY1&2VO HO1 I1 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1176 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 568 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 113,515,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83943 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 99 (estimated)
Safety Information
[ RIDADR ]:
UN 2811 6.1 / PGIII