2-Amino-6-methoxy-3H-pyrido(2,3-b)(1,4)thiazine

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Names

[ CAS No. ]:
37591-10-9

[ Name ]:
2-Amino-6-methoxy-3H-pyrido(2,3-b)(1,4)thiazine

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
398.6ºC at 760mmHg

[ Molecular Formula ]:
C8H9N3OS

[ Molecular Weight ]:
195.24200

[ Flash Point ]:
194.9ºC

[ Exact Mass ]:
195.04700

[ PSA ]:
85.80000

[ LogP ]:
1.32050

[ Index of Refraction ]:
1.715

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1195000
CHEMICAL NAME :
3H-Pyrido(2,3-b)(1,4)thiazine, 2-amino-6-methoxy-
CAS REGISTRY NUMBER :
37591-10-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H9-N3-O-S
MOLECULAR WEIGHT :
195.26
WISWESSER LINE NOTATION :
T66 BN ES GN DHJ CZ HO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-amino-6-methoxy-1H-pyridine-2-thione
  • 2-chloroacetonitrile

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 6-chloro-3H-pyrido[2,3-b][1,4]thiazin-2-amine
  • 2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine
  • 2-methyl-5-[3-(4-methylpiperazin-1-yl)propyl]-3H-pyrido[2,3-b][1,4]diazepin-4-one,hydrochloride
  • 7-Fluoro-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine
  • 7-chloro-2,3-dihydro-1h-pyrido[2,3-b][1,4]thiazine
  • 7-Bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine
  • N-(2-amino-6-fluorophenyl)-4-nitrobenzene-1-sulfonamide
  • 4-nitro-N-[(4R)-1,2-oxazolidin-4-yl]benzene-1-sulfonamide
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{[2-(propan-2-yl)cyclohexyl]carbamoyl}propanoic acid
  • 3-[2-(Morpholin-4-yl)-1,3-thiazol-5-yl]propanenitrile
  • 2-[2-(Dimethylamino)-3,4-difluorophenoxy]acetic acid
  • O-{[1-(1-phenyl-1H-pyrazol-4-yl)cyclopropyl]methyl}hydroxylamine
  • tert-butyl N-{2-chloro-5-[(3-hydroxyazetidin-3-yl)methyl]phenyl}carbamate
  • Tert-butyl 2-[3-(trifluoromethyl)pyridin-4-yl]piperazine-1-carboxylate
  • 1-[(5-Bromo-2-chlorophenyl)methyl]cyclopropane-1-carboxylic acid
  • 2-(1-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclobutaneamido}cyclopentyl)acetic acid
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