1-formylpyrrolidine

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Names

[ CAS No. ]:
3760-54-1

[ Name ]:
1-formylpyrrolidine

[Synonym ]:
formylpyrrolidine
pyrrolidinecarbaldehyde
N-Formylpyrrolidine
1-pyrrolidinecarboxaldehyde
Pyrrolidine-1-carboxaldehyde
1-Formylpyrrolidine
MFCD00003169
Prolinal
EINECS 223-175-7

Chemical & Physical Properties

[ Density]:
1.04 g/mL at 25 °C(lit.)

[ Boiling Point ]:
92-94 °C15 mm Hg(lit.)

[ Molecular Formula ]:
C5H9NO

[ Molecular Weight ]:
99.13110

[ Flash Point ]:
203 °F

[ Exact Mass ]:
99.06840

[ PSA ]:
20.31000

[ LogP ]:
0.81240

[ Index of Refraction ]:
n20/D 1.479(lit.)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Pyrrolidine
  • Formic Acid
  • carbon monoxide
  • Carbon dioxide
  • Formaldehyde
  • (E)-1-(2-phenylprop-1-en-1-yl)pyrrolidine
  • ethyl L-cysteinate
  • Ethyl formate
  • Chloroform

DownStream

  • 4-Methyl-2-thiophenecarbaldehyde
  • 3-Methylthiophene-2-aldehyde
  • 2,4-Dichlorobenzaldehyde
  • 1-Methylpyrrolidine
  • Benzenemethanol, a-(2-phenylethynyl)-
  • 1-nitropyrrolidine
  • 1-Phenyl-3-propyl-5-oxo-2-pyrazoline-4-carbaldehyde
  • 1-(4-methoxyphenyl)-3-pyrrolidin-1-ylprop-2-ene-1-thione
  • Pyrrolidine,1-(diphenylmethyl)-

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols.

J. Org. Chem. 68(25) , 9747-52, (2003)

N-Tritylprolinal (prepared in four steps from l-proline) shows a very high Felkin diastereoselectivity in its reaction with various nucleophiles, leading to a straightforward and highly stereoselectiv...

Synthesis and inhibitory activity of acyl-peptidyl-prolinalderivatives toward post-proline cleaving enzyme as nootropic agents.

J. Enzym. Inhib. 3(3) , 163-78, (1990)

Several prolinal derivatives were synthesized and examined for their inhibitory activity on post-proline cleaving enzymes from Flavobacterium meningosepticum and bovine brain and their possible proper...

Tyrosine hydroxylase deficiency in three Greek patients with a common ancestral mutation.

Mov. Disord 25(8) , 1086-90, (2010)

We present the clinical, biochemical, and molecular findings of three Greek patients with tyrosine hydroxylase (TH) deficiency. All patients presented with a severe clinical phenotype characterized by...


More Articles

Related Compounds

  • 2-Benzyl-1-formylpyrrolidine
  • ethyl 1-formylpyrrolidine-2-carboxylate
  • (2S)-1-[(2S)-1-formylpyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide
  • (S)-methyl 2-((S)-1-formylpyrrolidine-2-carbonylamino)-3-phenylpropanoate
  • 1-acetyl-2-formylpyrrolidine
  • 1-Pyrrolidinecarboxaldehyde, 2,5-bis(hydroxymethyl)-, (2R,5S)-rel- (9CI)
  • Dimethyl(quinolin-6-yl)phosphine oxide
  • (2,2-Difluoro-2-iodoethyl)benzene
  • 1-(1-Chloroisoquinolin-5-yl)ethan-1-one
  • RM3WH8YX73
  • (R)-3-(Aminooxy)butane-1-thiol
  • 1-methyl-N-pentyl-1H-indol-5-amine
  • 2-(5-Chloro-1,2,4-thiadiazol-3-yl)acetonitrile
  • 5-Chloro-7-fluoro-2-methylquinoxaline
  • 5-Chloro-6-methylthiazolo[5,4-b]pyridine
  • 3-Chloro-7-cyclopropylisoquinoline
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