Butanedioic acid,2,2,3,3-tetrafluoro-

Names

[ CAS No. ]:
377-38-8

[ Name ]:
Butanedioic acid,2,2,3,3-tetrafluoro-

[Synonym ]:
EINECS 206-820-7
MFCD00042430
Tetrafluoro-1,4-butanedioic Acid
Perfluorosuccinic Acid
2,2,3,3-tetrafluorobutanedioic acid
Tetrafluorosuccinic Acid
Perfluoro-1,4-butanedioic Acid

Chemical & Physical Properties

[ Density]:
1,4 g/cm3

[ Boiling Point ]:
150°C 15mm

[ Melting Point ]:
115-118 °C(lit.)

[ Molecular Formula ]:
C₄H₂F₄O₄

[ Molecular Weight ]:
190.05000

[ Flash Point ]:
150°C/15mm

[ Exact Mass ]:
189.98900

[ PSA ]:
74.60000

[ LogP ]:
0.42620

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN0725000

CHEMICAL NAME :: Succinic acid, tetrafluoro-

CAS REGISTRY NUMBER :: 377-38-8

BEILSTEIN REFERENCE NO. :: 1790197

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H2-F4-O4

MOLECULAR WEIGHT :: 190.06

WISWESSER LINE NOTATION :: QVXFFXFFVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,694,1955

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 11FYAN "Fluorine Chemistry, Volume III. Biological Effects of Organic Fluorides," Simons, J.H., ed., New York, Academic Press, Inc., 1963 Volume(issue)/page/year: 3,85,1963

Safety Information

[ Hazard Codes ]:
Xi: Irritant;C: Corrosive;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
3261

[ WGK Germany ]:
3

[ RTECS ]:
WN0725000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Tetrafluoroethylene
N,N,N-Triethylethanaminium cyanide
1,2-dichlorotetrafluorocyclobut-1-ene
hexafluorocyclobutene
(E)-2,2,3,3,4,5-hexafluorohex-4-en-1-ol
2,2,3,3,4,4,5,5-octafluoro-1-(trifluoromethyl)pyrrolidine
1,3,3,4,4-pentafluoro-2-methoxycyclobutene
3,4-bis(difluoromethylidene)-1,1,2,2-tetrafluorocyclobutane
Difluoroacetic acid

DownStream

dimethyl tetrafluorosuccinate
Diethyl 2,2,3,3-Tetrafluorosuccinate
tetrafluorosuccinyl
Tetrafluorosuccinic Anhydride

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

Butanedioic acid,2,2,3,3-tetramethyl-
Butanedioic acid,2,2,3,3-tetrahydroxy-
Butanedioic acid,2,2,3,3-tetramethyl-, 1,4-diethyl ester
chlorosulfuric acid 2,2,3,3-tetrafluoro-propyl ester
Propanoic acid, 2,2,3,3-tetrafluoro-3-methoxy
2,2,3,3-Tetrafluorobutane-1,4-diyl bis(trifluoromethanesulfonate)
56-Nitroso-vancomycin
rac-(2R,3S)-3-{[(prop-2-en-1-yloxy)carbonyl]amino}oxolane-2-carboxylic acid
Benzyl 3-cyano-3-methylpyrrolidine-1-carboxylate
2-acetamido-3-(4-methyl-4H-1,2,4-triazol-3-yl)propanoic acid
8-Bromo-9-fluoro-2,3,4,5-tetrahydro-1,4-benzoxazepine
benzyl N-[(6-hydroxypyridin-3-yl)methyl]carbamate
tert-butyl N-(prop-2-en-1-yl)-N-(2,2,2-trifluoroethyl)carbamate
2-(Methoxymethyl)-4-(trifluoroacetyl)morpholine-2-carboxylic acid
benzyl N-[(2-bromo-5-chlorophenyl)methyl]carbamate
Methyl 2-amino-3-(2-chloropyrimidin-4-yl)propanoate

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