SU 9516
Suppliers
Names
[ CAS No. ]:
377090-84-1
[ Name ]:
SU 9516
[Synonym ]:
Kinome_2853
2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-5-methoxy-, (3Z)-
(3Z)-3-(1H-Imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-2H-indol-2-one
SU9516
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
601.5±55.0 °C at 760 mmHg
[ Molecular Formula ]:
C13H11N3O2
[ Molecular Weight ]:
241.245
[ Flash Point ]:
317.6±31.5 °C
[ Exact Mass ]:
241.085129
[ PSA ]:
67.01000
[ LogP ]:
1.02
[ Appearance of Characters ]:
crystalline | brown
[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C
[ Index of Refraction ]:
1.696
[ Storage condition ]:
Store at +4°C
[ Water Solubility ]:
DMSO: ~17 mg/mL
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
J. Cell. Mol. Med. 18(10) , 2061-70, (2014)
Immunotherapy mediated by recombinant antibodies is an effective therapeutic strategy for a variety of cancers. In a previous study, we demonstrated that the fibroblast growth factor 1 (FGF-1)-specifi...
Mol. Pharmacol. 70(2) , 645-55, (2006)
Mechanisms of lethality of the three-substituted indolinone and putatively selective cyclin-dependent kinase (CDK)2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-on...
Cell Cycle 7(24) , 3789-90, (2008)
Ever since it emerged that cyclin-dependent protein kinases catalyzed cell cycle transitions and with cancer seen as "a disease of the cell cycle," people have pursued the aim of testing kinase inhibi...