Flurocitabine
Suppliers
Names
[ CAS No. ]:
37717-21-8
[ Name ]:
Flurocitabine
[Synonym ]:
5-fluoro-arabino-O2,O2'-cyclocytidine
Ro-21-0702
fluoroancitabine
5-Fluoro-2,2'-cyclocytidine
5-fluoro-arabino-2,2'-anhydro-cytidine
Fluorocitabin
5-Fluor-2,2'-cyclocytidin
AAFC
Chemical & Physical Properties
[ Density]:
2.11g/cm3
[ Boiling Point ]:
391.7ºC at 760mmHg
[ Molecular Formula ]:
C9H10FN3O4
[ Molecular Weight ]:
243.19200
[ Flash Point ]:
190.7ºC
[ Exact Mass ]:
243.06600
[ PSA ]:
100.59000
[ Index of Refraction ]:
1.813
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA5400000
- CHEMICAL NAME :
- Cytosine, 2,2'-anhydroarabino-5-fluoro-
- CAS REGISTRY NUMBER :
- 37717-21-8
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H10-F-N3-O4
- MOLECULAR WEIGHT :
- 243.22
- WISWESSER LINE NOTATION :
- T B556 AN CO GO IN HHTT&J D1Q EQ JZ KF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - normocytic anemia Blood - leukopenia
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,2657,1974