iopronic acid

Names

[ CAS No. ]:
37723-78-7

[ Name ]:
iopronic acid

[Synonym ]:
lopronic
Bilimiron
Bilimiro
lopronic acid

Chemical & Physical Properties

[ Density]:
2.149g/cm3

[ Boiling Point ]:
674.2ºC at 760mmHg

[ Molecular Formula ]:
C15H18I3NO5

[ Molecular Weight ]:
673.02100

[ Flash Point ]:
361.5ºC

[ Exact Mass ]:
672.83200

[ PSA ]:
84.86000

[ LogP ]:
4.03800

[ Index of Refraction ]:
1.67

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ES5615000
CHEMICAL NAME :
Butyric acid, 2-((2-(3-acetamido-2,4,6-triiodophenoxy)ethoxy)methyl )-
CAS REGISTRY NUMBER :
37723-78-7
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H18-I3-N-O5
MOLECULAR WEIGHT :
673.04
WISWESSER LINE NOTATION :
QVY2&1O2OR BI DI FI CMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1090 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
43FLAV "Burger's Medicinal Chemistry," 4th ed., Wolff, M.E., ed., New York, John Wiley & Sons, Inc., 1980 Volume(issue)/page/year: 4(3),1153,1980 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3300 mg/kg
SEX/DURATION :
female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978- Volume(issue)/page/year: 7,425,1984

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(2-chloroethoxy)-2-ethylpropionic acid ethyl ester
  • 3-(2-Jodaethoxy)-2-aethylpropionsaeureaethylester
  • 2-(2-Chloraethoxymethyl)-2-aethylmalonsaeurediaethylester
  • 3-[2-(3-Acetylamino-2,4,6-trijodophenoxy)-aethoxy]-2-aethylpropionsaeureaethylester

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Iopronic acid sodium salt
  • Octanethioic acid S-propyl ester
  • Hexanethioic acid S-decyl ester
  • Thiopropionic acid S-undecyl ester
  • trisporic acid
  • Benzenesulfonic acid, 3,3-methylenebis2,4(or 4,6)-dihydroxyphenyleneazobis-, potassium sodium salt
  • 3-(4-methoxyphenyl)-9-(pyridin-4-ylmethyl)-9,10-dihydrochromeno[8,7-e][1,3]oxazin-2(8H)-one
  • 3-Isobutyl-6-(5-methyl-3-isoxazolyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
  • N~2~-[4-(4-benzylpiperazino)-4-oxobutyl]-1H-indole-2-carboxamide
  • (5Z)-3-[3-(morpholin-4-yl)propyl]-5-(quinolin-8-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
  • 5-bromo-2-[(2-fluorobenzyl)sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
  • N-[1-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)propyl]-5-methoxy-1-methyl-1H-indole-2-carboxamide
  • N-{2-[(2,5-dimethoxyphenyl)amino]-2-oxoethyl}-1H-indole-2-carboxamide
  • 6-[(2E)-3-(dimethylamino)prop-2-enoyl]-7-hydroxy-8-methyl-4-propyl-2H-chromen-2-one
  • 9-isobutyl-3-phenyl-9,10-dihydrochromeno[8,7-e][1,3]oxazin-4(8H)-one
  • 3-(5-Bromo-3-pyridinyl)-6-(2-furyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
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