9H-Isoxazolo[3,2-b]quinazolin-9-one,2,3-dihydro-3-methyl-

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Names

[ CAS No. ]:
37795-71-4

[ Name ]:
9H-Isoxazolo[3,2-b]quinazolin-9-one,2,3-dihydro-3-methyl-

[Synonym ]:
9H-ISOXAZOLO(3,2-b)QUINAZOLIN-9-ONE,2,3-DIHYDRO-3-METHYL
3-methyl-2,3-dihydro-isoxazolo[3,2-b]quinazolin-9-one
EINECS 253-671-9
3-Methyl-2,3-dihydro-9H-isoxazolo(3,2-b)quinazolin-9-one
2,3-Dihydro-3-methyl-9H-isoxazolo(3,2-b)quinazolin-9-one
W 2451

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Boiling Point ]:
330.8ºC at 760mmHg

[ Molecular Formula ]:
C11H10N2O2

[ Molecular Weight ]:
202.20900

[ Flash Point ]:
153.9ºC

[ Exact Mass ]:
202.07400

[ PSA ]:
44.12000

[ LogP ]:
0.94220

[ Index of Refraction ]:
1.692

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NY3470000
CHEMICAL NAME :
9H-Isoxazolo(3,2-b)quinazolin-9-one, 2,3-dihydro-3-methyl-
CAS REGISTRY NUMBER :
37795-71-4
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C11-H10-N2-O2
MOLECULAR WEIGHT :
202.23
WISWESSER LINE NOTATION :
T C566 BVNO HNT&&J F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
765 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
670 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
860 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
243 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,164,1976

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • 3-chloro-2-methylpropanoyl chloride
  • Benzamide,2-amino-N-hydroxy-
  • Isatoic anhydride

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-ethyl-7-(oxolan-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 5-Bromo-4-nitropyridine-3-thiol