2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide
Names
[ CAS No. ]:
3785-01-1
[ Name ]:
2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide
[Synonym ]:
GNF-Pf-1399
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide
GNF-Pf-4643
4-[2-(1-ethylpyridin-1-ium-2-yl)ethenyl]-N,N-dimethylaniline,iodide
GNF-Pf-2708
MFCD00011994
EINECS 223-248-3
Chemical & Physical Properties
[ Melting Point ]:
267ºC (dec.)(lit.)
[ Molecular Formula ]:
C17H21IN2
[ Molecular Weight ]:
380.26700
[ Exact Mass ]:
380.07500
[ PSA ]:
7.12000
[ LogP ]:
0.23440
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU3971000
- CHEMICAL NAME :
- Pyridinium, 2-(p-(dimethylamino)styryl)-1-ethyl-, iodide
- CAS REGISTRY NUMBER :
- 3785-01-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H21-N2.I
- MOLECULAR WEIGHT :
- 380.30
- WISWESSER LINE NOTATION :
- T6KJ A2 B1U1R DN1&1 &I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02331
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
UU3971000
Articles
Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008)
The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-...
Science 334 , 1372-7, (2011)
Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic f...
Biochim. Biophys. Acta 1278(2) , 205-12, (1996)
The interaction of the fluorescent dye 2-(4-dimethylaminostyryl)-1-ethlypyridinium cation (DMP+) with cells of Escherichia coli AN120 (uncA) and AS-1 (acrA) was studied to elucidate the role of the en...