(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide

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Names

[ CAS No. ]:
3785-87-3

[ Name ]:
(E)-2-cyano-3-(4-dimethylaminophenyl)prop-2-enamide

[Synonym ]:
4-dimethylaminopiperidine-1-carboxylic acid tert-butyl ester
N-Boc-4-dimethylaminopiperidine

Chemical & Physical Properties

[ Density]:
1.203g/cm3

[ Boiling Point ]:
469.5ºC at 760 mmHg

[ Molecular Formula ]:
C12H13N3O

[ Molecular Weight ]:
215.25100

[ Flash Point ]:
237.8ºC

[ Exact Mass ]:
215.10600

[ PSA ]:
70.12000

[ LogP ]:
1.84518

[ Index of Refraction ]:
1.639

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GD7214200
CHEMICAL NAME :
Cinnamamide, alpha-cyano-p-(dimethylamino)-
CAS REGISTRY NUMBER :
3785-87-3
LAST UPDATED :
198512
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H13-N3-O
MOLECULAR WEIGHT :
215.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 14,1325,1965

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • p-Dimethylaminobenzaldehyde
  • 2-Cyanoacetamide
  • 2-Propenamide,3-amino-2-cyano-

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-(2-chlorophenyl)-2-cyano-3-[4-(1-cyanoethoxy)phenyl]prop-2-enamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 7,7-Difluoro-4-azaspiro[2.5]octane
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Ethyl 2-methyl-6-propan-2-ylpiperidine-3-carboxylate