(-)-Dexamethasone Acid

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Names

[ Name ]:
(-)-Dexamethasone Acid

[Synonym ]:
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.351g/cm3

[ Boiling Point ]:
566.865ºC at 760 mmHg

[ Melting Point ]:
274-277ºC

[ Molecular Formula ]:
C₂₁H₂₇FO₅

[ Molecular Weight ]:
378.43400

[ Flash Point ]:
296.63ºC

[ Exact Mass ]:
378.18400

[ PSA ]:
94.83000

[ LogP ]:
2.41890

[ Index of Refraction ]:
1.598

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Dexamethasone
11β,17α-dihydroxy-9α-fluoro-16α-methyl-3,20-dioxo-1,4-pregnadien-21-al

DownStream

(11β,16α,17α,11'β,16'α,17'α)-N,N'-(Disulfanediyldi-2,1-ethanediyl )bis(9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-1 7-carboxamide)
(11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxo-N-(2-sulfa nylethyl)androsta-1,4-diene-17-carboxamide

Related Compounds

Dexamethasone pivalate
Octanethioic acid S-propyl ester
Hexanethioic acid S-decyl ester
Thiopropionic acid S-undecyl ester
trisporic acid
Benzenesulfonic acid, 3,3-methylenebis2,4(or 4,6)-dihydroxyphenyleneazobis-, potassium sodium salt
5-(Piperidin-3-yl)piperazin-2-one
(3-Amino-2-cycloheptylpropyl)(methyl)amine
3-[(ethylamino)methyl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-5-amine
3-(cyanomethyl)-N-ethylbenzene-1-sulfonamide
methyl N-[3-(1-methyl-1H-pyrazol-4-yl)propyl]carbamate
1-(Ethoxymethyl)cyclobutane-1-sulfonamide
4-(Aminomethyl)-4-{[(propan-2-yl)amino]methyl}-1lambda6-thiane-1,1-dione
3-Ethyl-4-(4-fluoro-3-methylphenyl)pyrrolidin-3-amine
3-(3-Aminopyrrolidin-1-yl)-2,2-difluoropropanehydrazide
7a-phenyl-octahydro-1H-isoindol-4-amine

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