(-)-Dexamethasone Acid

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Names

[ CAS No. ]:
37927-01-8

[ Name ]:
(-)-Dexamethasone Acid

[Synonym ]:
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.351g/cm3

[ Boiling Point ]:
566.865ºC at 760 mmHg

[ Melting Point ]:
274-277ºC

[ Molecular Formula ]:
C21H27FO5

[ Molecular Weight ]:
378.43400

[ Flash Point ]:
296.63ºC

[ Exact Mass ]:
378.18400

[ PSA ]:
94.83000

[ LogP ]:
2.41890

[ Index of Refraction ]:
1.598

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Dexamethasone
  • 11β,17α-dihydroxy-9α-fluoro-16α-methyl-3,20-dioxo-1,4-pregnadien-21-al

DownStream

  • (11β,16α,17α,11'β,16'α,17'α)-N,N'-(Disulfanediyldi-2,1-ethanediyl )bis(9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-1 7-carboxamide)
  • (11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxo-N-(2-sulfa nylethyl)androsta-1,4-diene-17-carboxamide

Related Compounds

  • Dexamethasone pivalate
  • Octanethioic acid S-propyl ester
  • Hexanethioic acid S-decyl ester
  • Thiopropionic acid S-undecyl ester
  • trisporic acid
  • Benzenesulfonic acid, 3,3-methylenebis2,4(or 4,6)-dihydroxyphenyleneazobis-, potassium sodium salt
  • 2-((4-(benzo[d][1,3]dioxol-5-yl)-1-(p-tolyl)-1H-imidazol-2-yl)thio)-N-(p-tolyl)acetamide
  • (E)-3-((3-chloro-2-methylphenyl)amino)-3-((4-methylbenzyl)thio)-2-(phenylsulfonyl)acrylonitrile
  • 3-((4-isopropylphenyl)sulfonyl)-N-(p-tolyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine
  • (1-Ethyl-2-methyl-1-propen-1-yl)trimethylstannane
  • 5-(1-chloroethyl)-1H-imidazole
  • 6-ethoxy-3-((4-ethylphenyl)sulfonyl)-1-(4-methylbenzyl)quinolin-4(1H)-one
  • 2,3-Dichloro-N-methyl-4-(4-pyridinylmethoxy)benzenamine
  • 6,7-Dimethoxy-1-methyl-3-(4-methylbenzenesulfonyl)-1,4-dihydroquinolin-4-one
  • N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-1H-pyrazole-3-carboxamide
  • 3-((4-methoxyphenyl)sulfonyl)-6-methyl-1-propylquinolin-4(1H)-one
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