9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine

Names

[ Name ]:
9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine

[Synonym ]:
9-chloro azatadine
9-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
9-chloro-11-(1-methyl-piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
8-Dechloro-9-chloro-N-methyl Desloratadine

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁ClN₂

[ Molecular Weight ]:
324.84700

[ Exact Mass ]:
324.13900

[ PSA ]:
16.13000

[ LogP ]:
4.29900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-tert-butyl-3-methylpyridine-2-carboxamide
4-Chlorobenzyl chloride
magnesium,1-methylpiperidin-4-ide,chloride

DownStream

8-Dechloro-9-chloro Desloratadine
Loratadine Impurity 19

Related Compounds

1-[2-(3-Bromo-2-fluorophenyl)propan-2-yl]cyclopropan-1-amine
Methyl 2,5-diethyl-1,6-dioxaspiro[2.5]octane-2-carboxylate
2-Methoxy-2-(3-methylpyridin-4-yl)propan-1-amine
tert-butyl N-[5-(3-amino-1-hydroxypropyl)-2-hydroxyphenyl]carbamate
2,2-difluoro-2-(2-methyl-2H-indazol-3-yl)ethan-1-amine
Methyl 4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,3]oxazolidine]-4'-carboxylate
tert-butyl N-[(3R)-1-(1-hydroxypropan-2-yl)pyrrolidin-3-yl]carbamate
methyl (3R)-3-hydroxy-3-(6-methoxy-1,3-dioxaindan-5-yl)propanoate
2-[1-(Aminooxy)-2-methylpropan-2-yl]-4-bromo-6-fluorophenol
2-[3-(Aminomethyl)-2,2-dimethylcyclopropyl]-4-methylphenol

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