N-Methyl Desloratadine

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Names

[ CAS No. ]:
38092-89-6

[ Name ]:
N-Methyl Desloratadine

[Synonym ]:
8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
8-Chloro-5,6-dihydro-11H-benzo[5,6]Cyclohepto[1,2-b]pyridine-11-one
8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Loratadine Related Compound B
MFCD06411084
8-Chloroazatadine
5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-
8-Chloro-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Loratadine Impurity 7

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
474.3±45.0 °C at 760 mmHg

[ Melting Point ]:
106-109ºC

[ Molecular Formula ]:
C20H21ClN2

[ Molecular Weight ]:
324.847

[ Flash Point ]:
240.7±28.7 °C

[ Exact Mass ]:
324.139313

[ PSA ]:
16.13000

[ LogP ]:
5.69

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
-20?C Freezer

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

  • (3-(3-CHLOROPHENETHYL)PYRIDIN-2-YL)(1-METHYLPIPERIDIN-4-YL)METHANONE HYDROCHLORIDE
  • Loratadine Impurity 14
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • Loratadine Impurity 18
  • 3-[2-(3-CHLORO-PHENYL)-ETHYL]-PYRIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE
  • magnesium,1-methylpiperidin-4-ide,chloride
  • 2-Cyano-3-methylpyridine
  • Methanesulfonic acid
  • (1-Methyl-4-piperidinyl) {3[2-(3-chlorophenyl) ethyl ]2-pyridinyl} methanone
  • m-Chlorbenzyl chloride

DownStream

  • Loratadine
  • Desloratadine
  • Sch 37370

Related Compounds

  • 5,6-Dehydro-N-methyl Desloratadine
  • 8-Deschloro-8-bromo-N-methyl Desloratadine
  • 8-Dechloro-9-chloro-N-methyl Desloratadine
  • N-Methyl Iso Desloratadine
  • N-methyl-L-phenylalanyl-L-leucine methyl ester
  • N-methyl-3,3-diphenylcyclohexan-1-amine,hydrochloride
  • 2-(1E)-1-Buten-1-yl-5-chloro-1H-imidazole-4-carboxaldehyde
  • 3-(5-Chloro-2-methoxyanilino)-1-(4-nitrophenyl)-1-propanone
  • 1-(1,3-Benzodioxol-4-yl)-3-[(4-chlorophenyl)sulfanyl]-1-propanone
  • 1-(4-Methoxyphenyl)-4-[(2,3,4,5,6-pentamethylbenzyl)sulfanyl]-2-butanone
  • 1-(1,3-Benzodioxol-5-yl)-3-[(4-fluorophenyl)sulfanyl]-1-propanone
  • 2-({5-[3-(2,4-dichlorophenoxy)propyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(4-fluorophenyl)acetamide
  • N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}benzamide
  • 2,3-dimethoxy-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]benzamide
  • 4-methoxy-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)benzamide
  • 1-(Trifluoromethyl)-3-(3,3,3-trifluoropropyl)benzene
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