2-Chloro-5-fluoronicotinic acid

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Names

[ CAS No. ]:
38186-88-8

[ Name ]:
2-Chloro-5-fluoronicotinic acid

[Synonym ]:
3-Pyridinecarboxylic acid, 2-chloro-5-fluoro-
2-Chloro-5-fluoronicotinic acid
2-Chloro-5-fluoro-nicotinic acid
MFCD03092932

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
297.0±35.0 °C at 760 mmHg

[ Melting Point ]:
141-142ºC

[ Molecular Formula ]:
C6H3ClFNO2

[ Molecular Weight ]:
175.545

[ Flash Point ]:
133.4±25.9 °C

[ Exact Mass ]:
174.983627

[ PSA ]:
50.19000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.563

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
7/9-24/25-26-36/37-38-51

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • 2,6-Dichloro-5-fluoronicotinic acid
  • Ethyl 2-chloro-5-fluoronicotinate
  • (2E,4Z)-ethyl 2-cyano-5-(dimethylamino)-4-fluoro-penta-2,4-dienoate

DownStream

  • 2-Chloro-5-fluoronicotinonitrile
  • 2-Chloro-5-fluoropyridin-3-amine
  • 2-Chloro-5-fluoro-3-iodopyridine
  • METHYL2-CHLORO-5-FLUORONICOTINATE
  • 5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine
  • Ethyl 2-chloro-5-fluoronicotinate
  • 3-Bromo-5-fluoro-1H-pyrazolo[3,4-b]pyridine
  • 2-Amino-5-fluoronicotinic acid
  • 2-CHLORO-5-FLUORONICOTINAMIDE
  • 2-(3,4-difluoroanilino)-5-fluoropyridine-3-carboxylic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 2-Chloro-5-fluoronicotinic acid ethyl ester
  • 2-chloro-5-fluoronicotinic acid methyl ester
  • 2-chloro-6-[4-(ethoxycarbonyl)piperidin-1-yl]-5-fluoronicotinic acid
  • 4-Chloro-6-(methylamino)pyrimidine-5-carbaldehyde
  • (2-Chloro-5-formylphenyl)boronic acid
  • 2-Chloro-5-quinolinecarboxylic acid