11-Beta-hydroxyandrostenedione
Suppliers
Names
[ CAS No. ]:
382-44-5
[ Name ]:
11-Beta-hydroxyandrostenedione
[Synonym ]:
(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
Androst-4-ene-3,17-dione, 11β-hydroxy-
U 2826
Androst-4-ene-3,17-dione, 11-hydroxy-, (11β)-
11β-hydroxyandrost-4-ene-3,17-dione
(11β)-11-Hydroxyandrost-4-ene-3,17-dione
4-Androsten-11beta-ol-3,17-dione
11beta-Hydroxyandrostenedione
11β-Hydroxy-4-androsten-3,17-dione
11beta-Hydroxyandrost-4-ene-3,17-dione
Androst-4-ene-3,17-dione-11beta-ol
11b-Hydroxyandrost-4-ene-3,17-dione
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
475.3±45.0 °C at 760 mmHg
[ Melting Point ]:
197-199℃
[ Molecular Formula ]:
C19H26O3
[ Molecular Weight ]:
302.408
[ Flash Point ]:
255.4±25.2 °C
[ Exact Mass ]:
302.188202
[ PSA ]:
54.37000
[ LogP ]:
1.27
[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C
[ Index of Refraction ]:
1.569
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3.0
Synthetic Route
Articles
J. Steroid Biochem. Mol. Biol. 138 , 132-42, (2013)
• Etomidate inhibited DOC, deoxycortisol, A4 and T conversion in H295R cells. • CYP11B1 11β-hydroxylates A4 and T; CYP11B2 11β-hydroxylates T. • 11βHSD1 converts 11KA4 and 11KT; 11βHSD2 converts 11OHA...
Endocrinology 132(1) , 255-60, (1993)
Molecular oxygen is an obligatory substrate of all cytochrome P-450 (cyt P-450) hydroxylases involved in the steroid biosynthetic pathways. However, oxygen-derived free radicals are highly destructive...
Fertil. Steril. 72(6) , 996-1000, (1999)
To determine the sensitivity of 11beta-hydroxyandrostenedione (11-OHA4) and delta5-androstenediol (ADIOL) as markers of excessive adrenal androgen production.Prospective study.Academic medical centers...