4-Methyl-5-acetyl thiazole

Suppliers

Names

[ CAS No. ]:
38205-55-9

[ Name ]:
4-Methyl-5-acetyl thiazole

[Synonym ]:
5-Acetyl-4-methylthiazole
4-Methyl-5-acetyl-thiazol
1-(4-Methyl-1,3-thiazol-5-yl)ethanone
4-Methyl-5-acetyl thiazole
Ethanone, 1-(4-methyl-5-thiazolyl)-
5-Acetyl-4-methyl-thiazol

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
228.6±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C6H7NOS

[ Molecular Weight ]:
141.191

[ Flash Point ]:
92.0±21.8 °C

[ Exact Mass ]:
141.024841

[ PSA ]:
58.20000

[ LogP ]:
0.35

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.539

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934100090

Synthetic Route

Precursor & DownStream

Precursor

  • Thioformamide
  • 3-CHLORO-2,4-PENTANEDIONE
  • 5-Acetyl-4-methyl-2-thiazolamine
  • Isopentyl nitrite
  • 2,4-Pentandione
  • (Z)-Methanimidic acid
  • Ethanol

DownStream

  • Sulfurol
  • 1-(4-methyl-1,3-thiazol-5-yl)ethanol

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Simultaneous quantitation of chlormethiazole and two of its metabolites in blood and plasma by gas--liquid chromatography.

J. Chromatogr. A. 182(1) , 55-62, (1980)

A simple and rapid gas chromatographic method for the quantitation of chlormethiazole and two of its pharmacologically active metabolites, 5-acetyl-4-methylthiazole and 5-(1-hydroxyethyl)-4-methylthia...

The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites.

Br. J. Pharmacol. 129(1) , 95-100, (2000)

A single dose of clomethiazole (600 micromol kg(-1) i.p.) has previously been shown to be neuroprotective in the gerbil model of global ischaemia. In gerbils, clomethiazole (600 micromol kg(-1)) injec...


More Articles


Related Compounds

  • 2-Propylamino-4-methyl-5-acetyl thiazole hydrochloride
  • 2-phenyl-4-methyl-5-acetyl-thiazole hydrochloride
  • 4-methyl-5-acetyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
  • trans-4-methyl-5-acetyl-4-cyclohexenyl phenyl ketone
  • Sulfurol
  • Febuxostat impurity 8