1-(4-Chlorophenyl)piperazine

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Names

[ CAS No. ]:
38212-33-8

[ Name ]:
1-(4-Chlorophenyl)piperazine

[Synonym ]:
1-(p-chlorophenyl)piperazine
Piperazine,1-(4-chlorophenyl)
1-(4-chlorphenyl)piperazin
(4-chlorophenyl)piperazine
N-(p-chlorophenyl)piperazine
1-(4-ClPh)Pip
MFCD00044823
4-(4'-chlorophenyl)piperazine
1-(4-chloro-phenyl)-piperazine
p-Chlorophenylpiperazine

Chemical & Physical Properties

[ Density]:
1.159 g/cm3

[ Boiling Point ]:
113°C/0.27mm

[ Melting Point ]:
76-79 °C

[ Molecular Formula ]:
C10H13ClN2

[ Molecular Weight ]:
196.67700

[ Flash Point ]:
157.2ºC

[ Exact Mass ]:
196.07700

[ PSA ]:
15.27000

[ LogP ]:
2.14340

[ Index of Refraction ]:
1.557

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperazine
  • 4-Bromochlorobenzene
  • 1,4-Dichlorobenzene
  • tert-butyl 4-(4-chlorophenyl)piperazine-1-carboxylate
  • 1-(4-chlorophenyl)piperazine hydrochloride
  • Bis(2-Chloroethyl)amine hydrochloride
  • 4-Chloroaniline
  • dea
  • N-Boc-piperazine
  • 3-BROMO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDINE

DownStream

  • 3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridine
  • N-[(Z)-[1-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-2-oxoindol-3-ylidene]amino]-2-[4-(2-phenyl-1,8-naphthyridine-3-carbonyl)phenoxy]acetamide
  • 1-Piperazinepropanol,4-(4-chlorophenyl)-
  • 1-Piperazineethanol,4-(4-chlorophenyl)-a-(phenoxymethyl)-
  • 2-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-1-methylbenzo[e]benzimidazole
  • 1-[4-(4-chlorophenyl)piperazin-1-yl]-3-[4-(3-methyl-1H-indol-2-yl)phenoxy]propan-2-ol
  • 9-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-4-methyl-8,9-dihydropyrano[2,3-f]chromene-2,10-dione
  • (4-aminophenyl)-[4-(4-chlorophenyl)piperazin-1-yl]methanone
  • 1-Piperazineethanol, 4-(4-chlorophenyl)-alpha-[(4- methoxyphenoxy)methyl]-
  • 2-[4-(4-chlorophenyl)piperazin-1-yl]ethanol

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Central serotoninmimetic action of phenylpiperazines.

Pol. J. Pharmacol. Pharm. 32(4) , 495-504, (1980)

Studies of 1-(m-chlorophenyl)-piperazine (m-CPP), 1-(p-chlorophenyl)-piperazine (p-CPP) and 1-phenylpiperazine (PP) were carried out on rats, mice and rabbits in order to assess their stimulatory effe...

Comparative effects of p-chloroamphetamine and 1-(p-chlorophenyl)piperazine on 5-hydroxyindole concentration in rat brain.

Res. Commun. Chem. Pathol. Pharmacol. 29(1) , 201-4, (1980)

1-(p-Chlorophenyl)piperazine (PCPP), a structural analog of p-chloroamphetamine (PCA), increased serotonin and decreased 5-hydroxyindoleacetic acid (5-HIAA) concentration in rat brain at 6 hours. At o...


More Articles

Related Compounds

  • 1-(4-chlorophenyl)piperazine hydrochloride
  • 1-(4-Chlorophenyl)piperazine dihydrochloride
  • 1-[(4-chlorophenyl)methyl]piperazine-2,3-dione
  • 1-[(4-Chlorophenyl)phenylmethyl]piperazine-d8
  • 1-[(4-chlorophenyl)-phenylmethyl]piperazine,dihydrochloride
  • 1-(4-chlorophenyl)-2-piperazine-1-yl-ethanone