N-Hydroxy-N'-(3-pyridinyl)octanediamide

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Names

[ Name ]:
N-Hydroxy-N'-(3-pyridinyl)octanediamide

[Synonym ]:
S2190_Selleck
N-Hydroxy-N'-3-pyridinyloctanediamide
N-Hydroxy-N'-(pyridin-3-yl)octanediamide
N1-Hydroxy-N8-3-pyridinyl-octanediamide
Octanediamide, N-hydroxy-N-3-pyridinyl-
N-Hydroxy-N'-(3-pyridinyl)octanediamide
pyroxamide
N-Hydroxy-N'-3-pyridinyl octane diamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C₁₃H₁₉N₃O₃

[ Molecular Weight ]:
265.308

[ Exact Mass ]:
265.142639

[ PSA ]:
91.32000

[ LogP ]:
0.04

[ Appearance of Characters ]:
white to beige

[ Index of Refraction ]:
1.570

[ Storage condition ]:
?20°C

[ Water Solubility ]:
DMSO: soluble10mg/mL (clear solution)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

8-oxo-8-(3-pyridinylamino)-octanoic acid methyl ester
SUBERIC ACID MONOMETHYL ESTER

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).

Bioorg. Med. Chem. 23 , 5151-5, (2015)

Two of the histone deacetylases, TbDAC1 and TbDAC3, have been reported to be essential genes in trypanosomes. Therefore, we tested the activity of a panel of human histone deacetylase inhibitors (HDAC...

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