butyl(3-carboxypropyl)nitrosamine
Suppliers
Names
[ CAS No. ]:
38252-74-3
[ Name ]:
butyl(3-carboxypropyl)nitrosamine
[Synonym ]:
4-(N-Butyl-N-nitrosamino)butyric Acid
BCPN
N-Butyl-N-(3-carboxypropyl)nitrosamine
N-Nitrosobutylcarboxypropylamine
Chemical & Physical Properties
[ Density]:
1.12g/cm3
[ Boiling Point ]:
381.2ºC at 760mmHg
[ Melting Point ]:
41ºC
[ Molecular Formula ]:
C8H16N2O3
[ Molecular Weight ]:
188.22400
[ Flash Point ]:
184.4ºC
[ Exact Mass ]:
188.11600
[ PSA ]:
69.97000
[ LogP ]:
1.63470
[ Index of Refraction ]:
1.493
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ES8125000
- CHEMICAL NAME :
- Butyric acid, 4-(N-butyl-N-nitrosamino)-
- CAS REGISTRY NUMBER :
- 38252-74-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C8-H16-N2-O3
- MOLECULAR WEIGHT :
- 188.26
- WISWESSER LINE NOTATION :
- QV3N4&NO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3760 mg/kg/12W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 gm/kg/20W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4700 mg/kg/14W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4375 mg/kg/20W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - rat Kidney
- DOSE/DURATION :
- 50 mmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 13,2435,1992 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 17,51,1978
Safety Information
[ RTECS ]:
ES8125000
[ HS Code ]:
2922499990
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%