(His(3-Me)2)-LHRH trifluoroacetate salt

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Names

[ CAS No. ]:
38343-58-7

[ Name ]:
(His(3-Me)2)-LHRH trifluoroacetate salt

[Synonym ]:
(His(3-Me)2)-LHRH

Chemical & Physical Properties

[ Molecular Formula ]:
C56H77N17O13

[ Molecular Weight ]:
1196.32000

[ Exact Mass ]:
1195.59000

[ PSA ]:
461.27000

[ LogP ]:
1.11780

MSDS

Safety Information

[ WGK Germany ]:
3

Articles

Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.

PLoS Biol. 12(9) , e1001952, (2014)

Characterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reprod...

R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism.

PLoS ONE 8(7) , e69616, (2013)

Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of a...

Characterization of 12 GnRH peptide agonists - a kinetic perspective.

Br. J. Pharmacol. 173(1) , 128-41, (2016)

Drug-target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy an...


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Related Compounds

  • (His(1-Me)2)-LHRH trifluoroacetate salt
  • (D-Ser4,D-Trp6)-LHRH trifluoroacetate salt
  • (3-(4-Azidophenyl)propionyl1,D-Tyr(Me)2,Arg6,Arg8,Tyr-NH29)-Vasopressin trifluoroacetate salt
  • Abz-tBu-Gly-tBu-Gly-Asn(Me)2-Ala-Ser-Ser-Arg-Leu-3-nitro-Tyr-Arg-OH
  • Carbetocin Acetate
  • H-D-His(3-Me)-OH