2,2',3,3',4,4'-Hexachlorobiphenyl
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Names
[ CAS No. ]:
38380-07-3
[ Name ]:
2,2',3,3',4,4'-Hexachlorobiphenyl
[Synonym ]:
1,2,3-trichloro-4-(2,3,4-trichlorophenyl)benzene
Chemical & Physical Properties
[ Density]:
1.593 g/cm3
[ Boiling Point ]:
403.8ºC at 760 mmHg
[ Melting Point ]:
151°C
[ Molecular Formula ]:
C12H4Cl6
[ Molecular Weight ]:
360.87800
[ Flash Point ]:
198.9ºC
[ Exact Mass ]:
357.84400
[ LogP ]:
7.27400
[ Index of Refraction ]:
1.6270 (rough estimate)
[ Storage condition ]:
room temp
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV5357000
- CHEMICAL NAME :
- 1,1'-Biphenyl, 2,2',3,3',4,4'-hexachloro-
- CAS REGISTRY NUMBER :
- 38380-07-3
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H4-Cl6
- MOLECULAR WEIGHT :
- 360.86
- WISWESSER LINE NOTATION :
- GR BG CG DR BG CG DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 383 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - other changes Endocrine - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 51,265,1997
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 1470 mg/kg/21D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 36,81,1976 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 320 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 21,54A,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1280 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 21,54A,1980
Safety Information
[ Hazard Codes ]:
N
[ Risk Phrases ]:
33-50/53
[ Safety Phrases ]:
60-61