Methyl 3-methoxypropanoate

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Names

[ CAS No. ]:
3852-09-3

[ Name ]:
Methyl 3-methoxypropanoate

[Synonym ]:
methyl 3-methoxypropionate
Propanoic acid, 3-methoxy-, methyl ester
Methyl 3-methoxypropanoate
3-Methoxypropionic Acid Methyl Ester
EINECS 223-358-1
MFCD00059085
Methyl β-methoxypropionate

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
143.6±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H10O3

[ Molecular Weight ]:
118.131

[ Flash Point ]:
43.5±11.4 °C

[ Exact Mass ]:
118.062996

[ PSA ]:
35.53000

[ LogP ]:
0.19

[ Vapour Pressure ]:
5.3±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.391

[ Storage condition ]:
Flammables area

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UF5274000
CHEMICAL NAME :
Propionic acid, 3-methoxy-, methyl ester
CAS REGISTRY NUMBER :
3852-09-3
BEILSTEIN REFERENCE NO. :
1744829
LAST UPDATED :
199712
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C5-H10-O3
MOLECULAR WEIGHT :
118.15
WISWESSER LINE NOTATION :
1OV2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0486-0599
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3656 ppm/6H
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0486-0599
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(3),48,1974

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R10;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UF5274000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2918990090

Synthetic Route

Precursor & DownStream

Precursor

  • Methanol
  • acrylic acid methyl ester
  • β-Propiolactone
  • 1,2-EPOXYBUTANE
  • Methyl vinyl ketone
  • Sodium Methylate
  • Allyl alcohol
  • Pentan-3-ol
  • D-Menthol
  • (±)-2-Butanol

DownStream

  • Propanoic acid,3-methoxy-, pentyl ester
  • butan-2-yl 3-methoxypropanoate
  • 4-diethoxyphosphoryl-1-methoxypentan-3-one
  • OCTAFLUOROTETRAHYDROFURAN
  • Trifluoroacetyl fluoride
  • perfluorobutyryl fluoride
  • PERFLUOROMETHOXYPROPIONOYL FLUORIDE 98
  • 5-methylhex-5-enoic acid
  • Pentafluoropropionyl fluoride
  • Propanoic acid,3-methoxy-, butyl ester

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • methyl 3-imino-3-methoxypropanoate hydrochloride
  • methyl 3-bromo-2-methoxypropanoate
  • methyl 3-chloro-2-methoxypropanoate
  • methyl 3-(N-isopropylacetamido)-3-methoxypropanoate
  • methyl 3-(4-hydroxyphenyl)-2-methoxypropanoate
  • methyl 3,3-difluoro-3-methoxypropanoate