3-[(4-bromo-benzyloxyimino)-methyl]-rifamycin

Names

[ CAS No. ]:
38601-55-7

[ Name ]:
3-[(4-bromo-benzyloxyimino)-methyl]-rifamycin

[Synonym ]:
3-Formylrifamycin-SV-O-p-Brombenzyloxim

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Molecular Formula ]:
C45H53BrN2O13

[ Molecular Weight ]:
909.81200

[ Exact Mass ]:
908.27300

[ PSA ]:
222.90000

[ LogP ]:
7.20530

[ Index of Refraction ]:
1.641

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1758000
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 3-formyl-5,6,9, 17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-he ptamethyl-, 21-acetate, O-(4-bromo benzyl)oxime
CAS REGISTRY NUMBER :
38601-55-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C45-H53-Br-N2-O13
MOLECULAR WEIGHT :
909.91
WISWESSER LINE NOTATION :
T C6 B65-24- A D E 2BC G& AV LO NO F&VM OU B&U D&U MH&&&TJ DQ E1UNOR DE GQ IQ J1 M1 QO1 R1 SO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 17,396,1974

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Formyl Rifamycin

DownStream

Related Compounds

  • 3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)propanoic acid
  • 3-(4-Bromo-3-methyl-phenylsulfanylmethyl)-5-chloro-2-(4-chloro-phenoxymethyl)-benzo[b]thiophene
  • 3-(4-BROMO-1-METHYL-1H-PYRAZOL-5-YL)ANILINE
  • 3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenylamine
  • 3-(4-BROMO-5-METHYL-3-TRIFLUOROMETHYL-PYRAZOL-1-YL)-PROPIONIC ACID
  • 3-(4-BROMO-3-METHYL-PYRAZOL-1-YL)-PROPYLAMINE
  • 2-[N-(2,2-dimethylpropyl)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]acetic acid
  • 2-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methylpentanamido}butanoic acid
  • 1-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoyl]-4,4-difluoropyrrolidine-3-carboxylic acid
  • 2-[N-benzyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]acetic acid
  • 3-(2-Hydroxypropyl)-2,2-dimethyloxolane-3-carbaldehyde
  • 8-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]butanamido}octanoic acid
  • 3-[2-(4-formyl-3-methyl-1H-pyrazol-1-yl)phenyl]prop-2-ynoic acid
  • 1-[(Cyclohex-3-en-1-yl)methyl]cyclobutane-1-carbaldehyde
  • 2,2-Dimethyl-3-(thiolan-2-yl)propanal
  • 5-(3-Ethoxyphenyl)-2-ethylpiperidin-3-amine
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