2-(9-Oxoacridin-10(9H)-yl)acetic acid

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Names

[ CAS No. ]:
38609-97-1

[ Name ]:
2-(9-Oxoacridin-10(9H)-yl)acetic acid

[Synonym ]:
cridanimod
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid
MFCD00157050
(9-Oxo-10(9H)-acridinyl)acetic acid
9-Oxo-10(9H)-acridineacetic acid
(9-oxoacridin-10(9H)-yl)acetic acid
10-(Carboxymethyl)-9(10H)-acridone
2-(9-oxoacridin-10-yl)acetic acid
10(9H)-Acridineacetic acid, 9-oxo-
9-Oxoacridine-10-acetic Acid
10-(Carboxymethyl)-9(10H)acridone
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid (10-(Carboxymethyl)-9(10H)acridone

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
486.6±34.0 °C at 760 mmHg

[ Melting Point ]:
-289ºC (dec.)

[ Molecular Formula ]:
C15H11NO3

[ Molecular Weight ]:
253.253

[ Flash Point ]:
248.1±25.7 °C

[ Exact Mass ]:
253.073898

[ PSA ]:
59.30000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.657

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7190000
CHEMICAL NAME :
10(9H)-Acridineacetic acid, 9-oxo-
CAS REGISTRY NUMBER :
38609-97-1
BEILSTEIN REFERENCE NO. :
0227508
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H11-N-O3
MOLECULAR WEIGHT :
253.27
WISWESSER LINE NOTATION :
T C666 BN IVJ B1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
1022 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 6,408,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AR7190000

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

  • 9-Oxo-10-acridineacetic acid
  • ethyl 2-bromoacetate
  • Acridone
  • Cridanimod ethyl ester
  • 2-[N-(cyanomethyl)anilino]benzoic acid
  • N-(aminocarbonylmethyl)-N-phenylanthranilic acid
  • 2-[N-(carboxymethyl)anilino]benzoic acid
  • N-Phenylanthranilic acid
  • 2-Chlorobenzoic acid

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • Cridanimod sodium
  • 2-(9,10-dihydroanthracen-9-yl)acetic acid
  • 2-(9-oxoacridin-10-yl)ethyl carbonochloridate
  • 2-(9-oxoacridin-10-yl)ethyl N-methylcarbamate
  • 2-(9,10-methanoanthracen-9(10H)-yl)acetic acid
  • 2-(9,10-DIOXO-9,10-DIHYDRO-2-ANTHRACENYL)ACETIC ACID
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine