4-Chloro-p-fluorobutyrophenone

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Names

[ CAS No. ]:
3874-54-2

[ Name ]:
4-Chloro-p-fluorobutyrophenone

[Synonym ]:
Chloropfluorobutyrophenone
G-CHLORO-P-FLUOROBUTYROPHENONE
4-Chloro-4'-fluorobu
4-(p-Fluorophenyl)-4-oxobutyl chloride
4-Chloro-p-fluorobutyrophenone
4-CHLORO-4-FLUOROBUTYROPHENONE
4-chloro-1-(4-fluorophenyl)butan-1-one
EINECS 223-395-3
MFCD00001007
4-Chloro-4'-fluorobutyrophenone
4'-Fluoro-4-chlorobutyrophenone
4-(4-Fluorophenyl)-4-oxobutyl chloride
1-Butanone, 4-chloro-1-(4-fluorophenyl)-
4-fluorophenyl 3-chloropropyl ketone
3-(4-Fluorobenzoyl)propyl chloride
γ-Chloro-4-fluorobutyrophenone
4-Chloro-1-(4-fluorophenyl)-1-butanone
γ-Chloro-p-fluorobutyrophenone
p-Fluoro-γ-chlorobutyrophenone
3-(p-Fluorobenzoyl)propyl chloride
4-Fluorobenzoylpropyl chloride
p-Fluoro-4-chlorobutyrophenone

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
299.1±20.0 °C at 760 mmHg

[ Melting Point ]:
5-6 °C

[ Molecular Formula ]:
C10H10ClFO

[ Molecular Weight ]:
200.637

[ Flash Point ]:
134.7±21.8 °C

[ Exact Mass ]:
200.040421

[ PSA ]:
17.07000

[ LogP ]:
2.68

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.506

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
0.38 g/L (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane
  • Fluorobenzene
  • 4-Chlorobutyryl chloride
  • 4-Fluorophenylmagnesium bromide
  • 1-(4-chlorobut-1-yn-1-yl)-4-fluorobenzene

DownStream

  • 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane
  • MELPERONE
  • 1-Butanone,1-(4-fluorophenyl)-
  • Pipamperone
  • 1-(4-fluorophenyl)-4-(4-tritylpiperazin-1-yl)butan-1-one
  • 1-(4-FLUORO-PHENYL)-4-PIPERAZIN-1-YL-BUTAN-1-ONE
  • 5-(4-FLUOROPHENYL)-5-OXOVALERONITRILE
  • 1-(4-Chlorobutyl)-4-fluorobenzene
  • Cyclopropyl 4-fluorophenyl ketone
  • Cyclopropyl(4-methoxyphenyl)methanone

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one.

Bioorg. Med. Chem. 16 , 7291-301, (2008)

The synthesis and exploration of novel butyrophenones have led to the identification of a diazepane analogue of haloperidol, 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one (com...


More Articles

Related Compounds

  • 4-chloro-p-fluorobutyrophenone propylene ketal
  • 4-chloro-p-tropoquinone
  • 4-chloro-p-menthan-3-ol
  • 4-chloro-p-menthane
  • 4-chloro-p-menthan-3-one
  • Azobenzene, 4-chloro-
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine