cis-DICHLORO(o-PHENYLENEDIAMINE)-PLATINUM(II)

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Names

[ CAS No. ]:
38780-39-1

[ Name ]:
cis-DICHLORO(o-PHENYLENEDIAMINE)-PLATINUM(II)

Chemical & Physical Properties

[ Boiling Point ]:
257ºC at 760 mmHg

[ Molecular Formula ]:
C6H6Cl2N2Pt

[ Molecular Weight ]:
372.10900

[ Flash Point ]:
124.9ºC

[ Exact Mass ]:
370.95600

[ PSA ]:
24.06000

[ LogP ]:
3.09150

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2171500
CHEMICAL NAME :
Platinum(II), (1,2-benzenediamine-N,N')dichloro-, (SP-4-2)-
CAS REGISTRY NUMBER :
38780-39-1
LAST UPDATED :
199410
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H8-Cl2-N2-Pt
MOLECULAR WEIGHT :
374.15
WISWESSER LINE NOTATION :
ZR BZ &G-PT-G -Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes Tumorigenic - facilitates action of known carcinogen

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
5 umol/L
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 29,327,1980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Potassium tetrachloroplatinate(II)
  • o-Phenylenediamine

DownStream

Related Compounds

  • Platinum,dichloro(2-pyridinemethanamine-kN1,kN2)-, (SP-4-3)- (9CI)
  • cis-dichloro-((Me)(Ph2)phosphine)(carbonyl)platinum(II)
  • cis-dichloro-bis(di-n-butyl sulfide)-platinum(II)
  • cis-dichloro(1-phenyl-2,3-bis(diphenylphosphino)naphthalene)platinum(II)
  • cis-[platinum(II)dichloride(PPh2Me)2]
  • (4-chloro-o-phenylenediamine) dichloro platinum(II)
  • (3S,4R)-1-tert-butyl 3-methyl 4-(8-pivaloyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)pyrrolidine-1,3-dicarboxylate
  • Methyl 3-(bromomethyl)-4-fluorobenzo[b]thiophene-2-carboxylate
  • methyl 1-(3-aminopropyl)-1H-indole-5-carboxylate
  • Methyl 1-(2-carbamothioylethyl)pyrrolidine-2-carboxylate
  • Methyl 4-(4-bromobenzenesulfinyl)butanoate
  • (3-Methoxyphenyl)(pyridin-3-yl)methanamine
  • 2-Chloro-1-[2-(3-methoxyphenyl)pyrrolidin-1-yl]ethan-1-one
  • 2,2,2-trifluoroethyl N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]carbamate
  • 1-Methoxy-3-methyl-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
  • (3-Amino-3-phenylpropyl)(2-methoxyethyl)methylamine
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