Lapatinib (GW-572016) Ditosylate

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Names

[ CAS No. ]:
388082-77-7

[ Name ]:
Lapatinib (GW-572016) Ditosylate

[Synonym ]:
Tykerb Ditosylate
N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]quinazolin-4-amine 4-methylbenzenesulfonate (1:2)
acide 4-méthylbenzènesulfonique - N-{3-chloro-4-[(3-fluorobenzyl)oxy]phényl}-6-[5-({[2-(méthylsulfonyl)éthyl]amino}méthyl)furan-2-yl]quinazolin-4-amine (2:1)
Lapatinib (ditosylate)
Lapatinib Ditosylate
N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine bis(4-methylbenzenesulfonate)
4-QuinazolinaMine,N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-6-[5-[[[2-(Methylsulfonyl)ethyl]aMino]Methyl]-2-furanyl]-,4-Methylbenzenesulfonate (1:2)
Lapatinib ditasylate
Tyverb
Tykerb Ditosylat
4-Methylbenzolsulfonsäure--N-{3-chlor-4-[(3-fluorbenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]chinazolin-4-amin(2:1)
Tykerb
4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-, 4-methylbenzenesulfonate (1:2)
N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine 4-methylbenzenesulfonate (1:2)

Chemical & Physical Properties

[ Boiling Point ]:
750.7ºC at 760 mmHg

[ Melting Point ]:
240-242ºC

[ Molecular Formula ]:
C43H42ClFN4O10S3

[ Molecular Weight ]:
925.461

[ Flash Point ]:
407.8ºC

[ Exact Mass ]:
924.173584

[ PSA ]:
240.23000

[ LogP ]:
12.32880

[ Storage condition ]:
-20°C Freezer, Under Inert Atmosphere

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ HS Code ]:
29420000

Related Compounds

  • Lapatinib ditosylate hydrate
  • (5E)-5-hydroxyiminopentane-1,2,3,4-tetrol
  • Lapatinib-13C2,15N Ditosylate
  • Lapatinib-d7 ditosylate
  • Lapatinib impurity I
  • Lapatinib-d5
  • ({[2-(Trifluoromethyl)phenyl]methyl}carbamoyl)methyl 2,4-dichlorobenzoate
  • {[(4-Bromophenyl)methyl]carbamoyl}methyl 2,4-dichlorobenzoate
  • 2-((2,4-Difluorobenzyl)amino)-2-oxoethyl 2,4-dichlorobenzoate
  • {[(4-Ethylphenyl)methyl]carbamoyl}methyl 2,4-dichlorobenzoate
  • {[(3,4-Dimethylphenyl)methyl]carbamoyl}methyl 2,4-dichlorobenzoate
  • {[(4-Bromophenyl)methyl]carbamoyl}methyl 4-tert-butylbenzoate
  • {[(4-Ethylphenyl)methyl]carbamoyl}methyl 4-tert-butylbenzoate
  • {[(3,4-Dimethylphenyl)methyl]carbamoyl}methyl 4-tert-butylbenzoate
  • 2-((2,4-Difluorobenzyl)amino)-2-oxoethyl thiophene-2-carboxylate
  • 2-((4-Ethylbenzyl)amino)-2-oxoethyl thiophene-2-carboxylate
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