N-ACETYL COLCHINOL

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Names

[ CAS No. ]:
38838-26-5

[ Name ]:
N-ACETYL COLCHINOL

[Synonym ]:
Colchinol,N-acetyl-,methyl ether
N-acetylallocolchinol O-methyl ether
N-Acetylcolchinol methyl ether
N-acetylcolchinol
N-Acetylcolchinol O-methyl ether
N-acetylcolchcinol methyl ester

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
623.8ºC at 760 mmHg

[ Molecular Formula ]:
C20H23NO5

[ Molecular Weight ]:
357.40000

[ Flash Point ]:
331ºC

[ Exact Mass ]:
357.15800

[ PSA ]:
77.02000

[ LogP ]:
3.59930

[ Index of Refraction ]:
1.607

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH1000000
CHEMICAL NAME :
Colchinol, N-acetyl-
CAS REGISTRY NUMBER :
38838-26-5
LAST UPDATED :
199109
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H23-N-O5
MOLECULAR WEIGHT :
357.44
WISWESSER LINE NOTATION :
L B677 MH&T&J CO1 DO1 EO1 JMV1 MQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Blood - hemorrhage
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Mutation test systems - not otherwise specified
TYPE OF TEST :
Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
REFERENCE :
CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948- Volume(issue)/page/year: 3,134,1950

Precursor & DownStream

Precursor

DownStream

  • ZD6126
  • Colchinol, N-acetyl-, methyl ether

Related Compounds

  • N-acetyl β,β-dimethyl Cysteine Ethyl Ester
  • N-Acetyl-L-Tyr-L-Ala-OH
  • N-ACETYL-MET-ASP-ARG-VAL-LEU-SER-ARG-TYR ACETATE
  • N-acetyl-S-2-thenoyl cysteine
  • N-Acetyl-N-(2-methylphenyl)glycine
  • N-Acetyl-L-Cysteine Methyl Ester
  • 1-methyl-3-(1-methyl-1H-pyrazol-5-yl)-1H-pyrazole-4-carbaldehyde
  • 5-fluoro-6-methoxy-1H-indole-3-carboxylic acid
  • 3-(3-Fluorophenyl)pyrrolidine-3-carboxylic acid
  • Methyl 8-fluoro-1,2,3,4-tetrahydroisoquinoline-4-carboxylate
  • Tert-butyl 4-amino-3-(difluoromethyl)butanoate
  • Perfluoro-2-{2,3-bis[2-(fluorosulfonyl)ethoxy]propoxy}propanoyl fluoride
  • 5-Cycloheptyl-1,2-oxazole-4-carboxylic acid
  • ethyl 5-amino-4-cyclopropyl-1-methyl-1H-pyrazole-3-carboxylate
  • methyl 5-amino-4-cyclopropyl-1-ethyl-1H-pyrazole-3-carboxylate
  • (1-{2-[Methyl(propan-2-yl)amino]ethyl}cyclohexyl)methanamine
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