N-Hydroxyethylphthalimide

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Names

[ CAS No. ]:
3891-07-4

[ Name ]:
N-Hydroxyethylphthalimide

[Synonym ]:
EINECS 223-434-4
2-(2-Hydroxyethyl)isoindoline-1,3-dione
1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)-
N-hydroethyl phthalimide
MFCD00005903
2-(2-Hydroxyethyl)-1H-isoindole-1,3(2H)-dione
2-Phthalimidoethanol
N-Hydroxyethylphthal
2-hydroxyethylphthalimide
N-(2-Hydroxyethyl)phthalimide
Phthalimide, N-(2-hydroxyethyl)-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
356.5±25.0 °C at 760 mmHg

[ Melting Point ]:
126-128 °C(lit.)

[ Molecular Formula ]:
C10H9NO3

[ Molecular Weight ]:
191.183

[ Flash Point ]:
169.4±23.2 °C

[ Exact Mass ]:
191.058243

[ PSA ]:
57.61000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.622

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S26-S36/37/39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Precursor

  • Phthalic anhydride
  • 2-Aminoethanol
  • 2-[2-(oxan-2-yloxy)ethyl]isoindole-1,3-dione
  • hydroxyethyl bromide
  • Potassium phthalimide
  • N-(2-Bromoethyl)phthalimide
  • ACETAMIDE, N-(2-HYDROXY-4-NITROPHENYL)-
  • Acetamide,N-(2-hydroxy-5-nitrophenyl)-
  • 2-Chloroethanol
  • N-(2-Oxoethyl)phthalimide

DownStream

  • T56 BVNVJ C1
  • N-Vinylphthalimide
  • N-Phthaloylglycine
  • 1H-Isoindole-1,3(2H)-dione,2-(2-azidoethyl)-
  • N-(2-Oxoethyl)phthalimide
  • 2-Chloroethanamine hydrochloride
  • 2-[2-(2-Methoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione
  • Amlodipine intermediate
  • Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Purine acyclic nucleosides. Nitrogen isosteres of 9-[(2-hydroxyethoxy)methyl]guanine as candidate antivirals.

J. Med. Chem. 24(12) , 1528-31, (1981)

A number of nitrogen analogues of 9-[(2-hydroxyethoxy)methyl]guanine [acylovir, Zovirax] containing amine functions in the side chain were synthesized and tested for antiviral activity. These purine a...

Molluscicidal activity of synthetic derivatives of 2-hydroxyethylphthalimide.

Rev. Bras. Biol. 40(3) , 635-7, (1980)


More Articles


Related Compounds

  • N-Hydroxyethylphthalimide
  • N-tert-butyl-3-nitroaniline
  • N-octanoyl benzotriazole
  • N,N-Dimethylcarbamic acid m-isopropylphenyl ester
  • N-(diaminomethylidene)pyrrolidine-1-carboximidamide,hydrochloride
  • (-)-N-(1-Methylethyl)phosphoramidothioic acid O-methyl O-(2,4-dichlorophenyl) ester