2,8-dichlorodibenzo-4-dioxin

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Names

[ Name ]:
2,8-dichlorodibenzo-4-dioxin

[Synonym ]:
2,8-dichlorodibenzo-p-dioxin
2,8-Dichloro-dibenzofuran
Dibenzofuran,8-dichloro
2,8-dichlorodibenzodioxin
Dibenzofuran,2,8-dichloro
2,8-Dichlor-dibenzofuran
2,8-dichlorobenzo-p-dioxin

Chemical & Physical Properties

[ Density]:
1.47g/cm3

[ Boiling Point ]:
350.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₆Cl₂O₂

[ Molecular Weight ]:
253.08100

[ Flash Point ]:
140.2ºC

[ Exact Mass ]:
251.97400

[ PSA ]:
18.46000

[ LogP ]:
4.89140

[ Index of Refraction ]:
1.642

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP3150000

CHEMICAL NAME :: Dibenzo-p-dioxin, 2,8-dichloro-

CAS REGISTRY NUMBER :: 38964-22-6

LAST UPDATED :: 199510

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H6-Cl2-O2

MOLECULAR WEIGHT :: 253.08

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 847 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 14,649,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >300 mg/kg

TOXIC EFFECTS :: Endocrine - changes in thymus weight

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ RIDADR ]:
UN 3077

Related Compounds

2,8-dibromooxanthrene
2-[8-(4-chlorophenyl)-10-oxa-7-azabicyclo[4.4.0]deca-2,4,7,11-tetraen- 4-yl]propanoic acid
2,3-dichloro-7-nitrodibenzo-4-dioxin
2,7/2,8-Dichlorodibenzo-P-Dioxin Isomer Pair (13C12, 99%) 50 Ug/Ml In Nonane
1,2,8,9-TETRACHLORODIBENZO-PARA-DIOXIN
ethyl 2-[8-(4-methylphenyl)-10-oxa-7-azabicyclo[4.4.0]deca-2,4,7,11-te traen-4-yl]acetate
(S)-tert-butyl 3-((4,6-dimethylpyrimidin-2-yl)oxy)piperidine-1-carboxylate
tert-Butyl 3-(2-((4,6-dimethylpyrimidin-2-yl)oxy)ethyl)piperidine-1-carboxylate
tert-Butyl 4-(2-((4,6-dimethylpyrimidin-2-yl)oxy)ethyl)piperidine-1-carboxylate
tert-Butyl 2-(3-((4,6-dimethylpyrimidin-2-yl)oxy)propyl)piperidine-1-carboxylate
tert-Butyl 3-(3-((4,6-dimethylpyrimidin-2-yl)oxy)propyl)piperidine-1-carboxylate
(S)-tert-butyl (1-(4-chloro-6-methylpyrimidin-2-yl)pyrrolidin-3-yl)carbamate
(R)-tert-butyl (1-(4-chloro-6-methylpyrimidin-2-yl)pyrrolidin-3-yl)carbamate
Tert-butyl (1-(4-chloro-6-methylpyrimidin-2-yl)piperidin-3-yl)carbamate
Tert-butyl ((1-(4-chloro-6-methylpyrimidin-2-yl)piperidin-3-yl)methyl)carbamate
Tert-butyl ((1-(4-chloro-6-methylpyrimidin-2-yl)pyrrolidin-2-yl)methyl)carbamate

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