(Leu15)-Gastrin I (human)

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Names

[ CAS No. ]:
39024-57-2

[ Name ]:
(Leu15)-Gastrin I (human)

[Synonym ]:
[Leu15]-Gastrin I (human)

Chemical & Physical Properties

[ Molecular Formula ]:
C₉₈H₁₂₆N₂₀O₃₁

[ Molecular Weight ]:
2080.16000

[ Exact Mass ]:
2078.89000

[ PSA ]:
804.61000

[ LogP ]:
3.65640

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Articles

[Syntheses of human little gastrin-I and its leucine-15, norleucine-15 and methoxinine-15 analogs].

Hoppe. Seylers. Z. Physiol. Chem. 364 , 157, (1983)

Human little gastrin-I is known to exhibit a high tendency to air-oxidation of its methionine-15 residue to the corresponding S-oxide derivative, with concomitant loss of biological activity. Since it...

Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.

Cancer Res. 57 , 1377, (1997)

Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue ...

Gastrin does not stimulate growth of the rat pancreas.

Scand. J. Gastroenterol. 31 , 404-410, (1996)

Gastrin is thought to stimulate growth of the pancreas via gastrin/cholecystokinin (CCK)-B-type receptors. The aim of the present study was to examine the trophic response of the pancreas to exogenous...

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