PD0325901

Suppliers

Names

[ CAS No. ]:
391210-10-9

[ Name ]:
PD0325901

[Synonym ]:
N-[(2R)-2,3-dihydroxyproposy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide
PD 0325901
N-[(R)-2,3 -Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide
PD0325901

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Melting Point ]:
112-114ºC

[ Molecular Formula ]:
C16H14F3IN2O4

[ Molecular Weight ]:
482.193

[ Exact Mass ]:
481.995026

[ PSA ]:
90.82000

[ LogP ]:
6.16

[ Appearance of Characters ]:
white to off-white

[ Index of Refraction ]:
1.645

[ Storage condition ]:
Store at -20°C

[ Water Solubility ]:
DMSO: soluble20mg/mL, clear

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H373-H410

[ Precautionary Statements ]:
P273-P301 + P310 + P330-P391-P501

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
25-48-50

[ Safety Phrases ]:
22-36/37/39-61

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

Precursor & DownStream

Precursor

  • 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
  • (S)-N-CARBOBENZYLOXYCYCLOHEXYLALANINOL
  • N-{[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}-3,4-difluoro-2-[(2-fluoro-4-iodo-phenyl)amino]benzamide

DownStream

Articles

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Mol. Ther. 23 , 952-63, (2015)

The advent of induced pluripotent stem cells--generated via the ectopic overexpression of reprogramming factors such as OCT4, SOX2, KLF4, and C-MYC (OSKM) in a differentiated cell type--has enabled gr...

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Related Compounds

  • Methyl 2-bromo-4-fluoro-5-(fluorosulfonyl)benzoate
  • 4-(1-Ethoxyethenyl)-3-fluorophenol
  • Tert-butyl 2-formyl-1,4-oxazepane-4-carboxylate
  • 2-(2,2,2-Trifluoroethoxy)ethane-1-sulfinamide
  • 1,3-Dichloropropane-2-sulfinamide
  • 2-Methoxy-2-methylhept-3-en-1-amine
  • 1-Nitrohept-3-ene
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,3-dimethylbutanamido]butanoic acid
  • Ethyl 3-(thiazol-5-yl)propanoate
  • 2(1H)-Pyridinone, 5,6-dihydro-3-[2-(2-methylphenyl)hydrazinyl]-
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