Sodium chloroacetate
Suppliers
Names
[ CAS No. ]:
3926-62-3
[ Name ]:
Sodium chloroacetate
[Synonym ]:
sodium 2-chloroacetate
Chloroacetic acid, sodium salt
Sodium monochloroacetate
SMA
Acetic acid, 2-chloro-, sodium salt (1:1)
Chloroacetic acid sodium salt
EINECS 223-498-3
Sodium chloroacetate
sodium,2-chloroacetate
MFCD00002684
Chemical & Physical Properties
[ Density]:
1.399g/cm3
[ Boiling Point ]:
189ºC at 760 mmHg
[ Melting Point ]:
199 °C (dec.)(lit.)
[ Molecular Formula ]:
C2H2ClNaO2
[ Molecular Weight ]:
116.479
[ Flash Point ]:
270°C
[ Exact Mass ]:
115.964104
[ PSA ]:
40.13000
[ Index of Refraction ]:
1.438
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
440 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG1400000
- CHEMICAL NAME :
- Acetic acid, chloro-, sodium salt
- CAS REGISTRY NUMBER :
- 3926-62-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C2-H2-Cl-O2.Na
- MOLECULAR WEIGHT :
- 116.48
- WISWESSER LINE NOTATION :
- QV1G &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,78,1941
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 165 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 86,336,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 156 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,1047,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 99 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,78,1941
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 31(12),53,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 81 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,1047,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity Gastrointestinal - hypermotility, diarrhea Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- NVTMAF Nordisk Veterinaermedicin Danske Udgave. (Copenhagen, Denmark) Volume(issue)/page/year: 13,271,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - domestic
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - coma Gastrointestinal - other changes
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 18,179,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5400 mg/kg/90D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in leukocyte (WBC) count
- REFERENCE :
- TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 67,171,1991
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H319-H400
[ Precautionary Statements ]:
P273-P301 + P310-P305 + P351 + P338
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R25;R38;R50
[ Safety Phrases ]:
S22-S37-S45-S61
[ RIDADR ]:
UN 2659 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
AG1400000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2915400090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915400010
[ Summary ]:
2915400010 sodium 2-chloroacetate。Supervision conditions:None。VAT:17.0%。Tax rebate rate:0.0%。Lowest tariff:5.5%。General tariff:30.0%
Articles
Environ. Mol. Mutagen. 51(8-9) , 871-8, (2010)
The haloacetic acids (HAAs) are disinfection by-products (DBPs) that are formed during the disinfection of drinking water, wastewaters and recreational pool waters. Currently, five HAAs [bromoacetic a...
Chem. Biol. Interact. 225 , 1-12, (2015)
Chloroacetic acid (CA), a chlorinated analog of acetic acid and an environmental toxin that is more toxic than acetic, dichloroacetic, or trichloroacetic acids, is widely used in chemical industries. ...
PLoS ONE 9(4) , e94685, (2014)
We report a novel electrochemical immunosensor that can sensitively detect avian influenza virus H5 subtype (AIV H5) captured by graphene oxide-H5-polychonal antibodies-bovine serum albumin (GO-PAb-BS...