10-[3-(dimethylamino)propyl]phenothiazin-2-ol

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Names

[ CAS No. ]:
3926-64-5

[ Name ]:
10-[3-(dimethylamino)propyl]phenothiazin-2-ol

[Synonym ]:
2-hydroxypromazine
2-Hydroxy-10(3'-dimethylaminopropyl)phenothiazin
10-(3-dimethylamino-propyl)-10H-phenothiazin-2-ol
Hydroxypromazin
2-Hydroxy-10-(3-(dimethylamino)propyl)phenothiazine
Phenothiazine,10-(3-(dimethylamino)propyl)-2-hydroxy
N-<3-Dimethylamino-propyl>-2-hydroxy-phenothiazin
2-Hydroxypromazin

Chemical & Physical Properties

[ Density]:
1.204g/cm3

[ Boiling Point ]:
479.4ºC at 760 mmHg

[ Molecular Formula ]:
C17H20N2OS

[ Molecular Weight ]:
300.41900

[ Flash Point ]:
243.8ºC

[ Exact Mass ]:
300.13000

[ PSA ]:
52.01000

[ LogP ]:
4.01160

[ Index of Refraction ]:
1.639

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO7525000
CHEMICAL NAME :
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-hydroxy-
CAS REGISTRY NUMBER :
3926-64-5
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H20-N2-O-S
MOLECULAR WEIGHT :
300.45
WISWESSER LINE NOTATION :
T C666 BN ISJ B3N1&1 EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 4,2425,1965

Safety Information

[ HS Code ]:
2934300000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chlorpromazine
  • 3-Chloro-N,N-dimethylpropan-1-amine
  • Chlorpromazine hydrochloride

DownStream

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 7-chloro-10-[3-(dimethylamino)propyl]phenothiazin-2-ol
  • 8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-2-ol
  • 8-Chloro-10-[3-(dimethylamino)propyl]-3-methoxy-10H-phenothiazin-2-ol
  • 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]-2-morpholin-4-ylethanol
  • Propionylpromazine
  • Propionylpromazine hydrochloride
  • (-)-Flutriafol
  • Ethyl 1-(Bromomethyl)-4-methylenecyclohexanecarboxylate
  • 4-(3-Thienyl)-1H-pyrrole-3-carboxylic acid methyl ester
  • 5,7-Dichloro-1H-benzimidazole-2-carboxylic acid
  • 3-(1-Methyl-1h-pyrazol-4-yl)-N-(3-methyl-1,2,4-thiadiazol-5-yl)-imidazo[1,2-a]pyrazin-8-amine
  • 2-(7-nitro-3,4-dihydroisoquinolin-2(1H)-yl)ethanol
  • (1R,3R,5S)-3-Phenyl-8-azabicyclo[3.2.1]octane
  • 5-Sec-butylbenzofuran-2-carbaldehyde
  • 1-pentyl-1H-benzotriazole-5-carboxylic acid
  • 1-(6-nitro-2H-chromen-3-yl)ethan-1-one
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