2-Fluorobenzoyl chloride

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Names

[ CAS No. ]:
393-52-2

[ Name ]:
2-Fluorobenzoyl chloride

[Synonym ]:
2-Fluorobenzoyl
2-Fluorbenzoylchlorid
MFCD00000656
2-fluoro-benzoylchlorid
EINECS 206-887-2
Benzoyl chloride, 2-fluoro-
2-fluorobenzoic acid chloride
o-fluoro-benzoylchlorid
ortho-fluorobenzoyl chloride
2-fluoro-benzoyl chloride
o-Fluorobenzoyl
2-Fluorobenzoyl chlo
O-FLUOROBENZOYL CHLORIDE
2-Fluoro benzoyl chloride
2-Fluorobenzoyl chloride

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
203.7±0.0 °C at 760 mmHg

[ Melting Point ]:
4 °C(lit.)

[ Molecular Formula ]:
C7H4ClFO

[ Molecular Weight ]:
158.557

[ Flash Point ]:
82.2±0.0 °C

[ Exact Mass ]:
157.993469

[ PSA ]:
17.07000

[ LogP ]:
1.84

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.520

[ Storage condition ]:
Refrigerator, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM6640000
CHEMICAL NAME :
Benzoyl chloride, o-fluoro-
CAS REGISTRY NUMBER :
393-52-2
BEILSTEIN REFERENCE NO. :
0636864
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H4-Cl-F-O
MOLECULAR WEIGHT :
158.56
WISWESSER LINE NOTATION :
GVR BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5(Suppl 1),3,1983

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
DM6640000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29163900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Fluorobenzoic acid
  • 2-(4,5-dihydro-1,3-oxazol-2-yl)aniline

DownStream

  • 5-(2-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione
  • (2-Fluorophenyl)(4-fluorophenyl)methanone
  • 2-(2-FLUOROBENZAMIDO)ACETIC ACID
  • Biphenyl
  • 2-Fluorobenzophenone
  • 3-hydroxy-9H-9-xanthenone
  • 3-(2-Fluorophenyl)-3-oxopropanenitrile
  • Ethyl 2-fluorobenzoate
  • 2-Fluoroaniline
  • METHYL 2-FLUOROBENZOATE

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 2-fluorobenzoyl chloride oxime
  • 5-bromo-2-fluorobenzoyl chloride
  • 5-Amino-2-fluorobenzoyl chloride
  • 2-bromo-2-fluorobenzoyl chloride
  • 4-nitro-2-fluorobenzoyl chloride
  • 3-Bromo-2-fluorobenzoyl chloride
  • 2-Hydroxy-3-methyl-3-phenylbutanoic acid
  • 1-(trans-4-Ethylcyclohexyl)-3,5-difluorobenzene
  • 1-Methyl-3-(2-thiazolyl)-1H-indole
  • 2-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]piperidine
  • 2-formylcyclopent-2-ene-1-carboxylic Acid
  • 2-(4-Nitrophenyl)cyclopropane-1-carboxylic acid
  • 2-(2-Bromopropyl)-1,3-dimethylbenzene
  • N-tert-Butoxycarbonyl-N-(3,5-dimethylphenyl)aniline
  • 1-(4-Methoxyphenyl)-4-propylpiperazine
  • 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
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