2-Fluoronicotinic acid

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Names

[ CAS No. ]:
393-53-3

[ Name ]:
2-Fluoronicotinic acid

[Synonym ]:
3-Fluoropyridine-4-Carboxylic Acid
3-Pyridinecarboxylic acid, 2-fluoro-
3-Fluoroisonicotinic acid
3-Fluoro-4-pyridinecarboxylic acid
2-Fluoronicotinic acid
3-Fluor-isonicotinsaeure
3-fluoro-pyridine-4-carboxylic acid
4-Pyridinecarboxylic acid, 3-fluoro-
MFCD03789251
T6NJ BF CVQ
3-Fluoro-isonicotinic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
360.0±22.0 °C at 760 mmHg

[ Melting Point ]:
251-254°C (dec.)

[ Molecular Formula ]:
C6H4FNO2

[ Molecular Weight ]:
141.100

[ Flash Point ]:
171.5±22.3 °C

[ Exact Mass ]:
141.022614

[ PSA ]:
50.19000

[ LogP ]:
0.49

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.542

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbon dioxide
  • 3-Fluoropyridine
  • 3-Fluor-4-methylpyridin
  • 3-Amino-4-methylpyridine
  • 2-Chloro-4-methyl-5-nitropyridine
  • 2-Hydroxy-4-methyl-5-nitropyridine
  • 2-Amino-5-nitro-4-picoline
  • 2-Amino-3-nitro-4-picoline
  • 4-Methyl-3-nitro-2-pyridinol
  • 2-Chloro-4-methyl-3-nitropyridine

DownStream

  • 3-Fluoropyridine
  • (3-Fluoropyridin-4-yl)methanol
  • 3-Fluoropyridine-4-carboxylic acid ethyl ester
  • methyl 3-fluoroisonicotinate
  • 3-((2-FLUORO-4-IODOPHENYL)AMINO)ISONICOTINIC ACID
  • 3-Fluoroisonicotinoyl chloride

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The effect of long-term administered CRAC channels blocker on the functions of respiratory epithelium in guinea pig allergic asthma model.

Gen. Physiol. Biophys. 34(2) , 167-76, (2015)

Previously, therapeutic potency of CRAC channels blocker was evidenced as a significant decrease in airway smooth muscle hyperreactivity, antitussive and anti-inflammatory effects. The major role of t...


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Related Compounds

  • 2-Fluoronicotinic acid
  • 6-BroMo-2-fluoronicotinic acid
  • 4-Bromo-2-fluoronicotinic acid
  • 5-Bromo-2-fluoronicotinic acid
  • 6-Chloro-2-fluoronicotinic acid
  • 5-Chloro-2-fluoronicotinic acid
  • 6-(1H-indol-3-yl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide
  • (R)-1-(4-Methylpyridin-2-yl)ethan-1-amine
  • 2-[3-(4-fluorophenyl)-6-oxo-1(6H)-pyridazinyl]-N-(2-methoxyethyl)acetamide
  • 2-[3-(4-fluorophenyl)-6-oxopyridazin-1(6H)-yl]-N-(3-methoxypropyl)acetamide
  • 2-[3-(3-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]-N-(pyridin-3-yl)acetamide
  • 2-[3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]-N-(pyridin-3-yl)acetamide
  • N-(2-methoxyethyl)-2-[3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl]acetamide
  • 2-(3-(4-methoxyphenyl)-6-oxopyridazin-1(6H)-yl)-N-(3-methoxypropyl)acetamide
  • 2-[3-(2-fluorophenyl)-6-oxo-1(6H)-pyridazinyl]-N-(2-furylmethyl)acetamide
  • N-(5-((2-morpholinoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclobutanecarboxamide
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