sPLA2 inhibitor 1
Suppliers
Names
[ CAS No. ]:
393569-31-8
[ Name ]:
sPLA2 inhibitor 1
[Synonym ]:
KH064
Benzenepentanoic acid, γ-[(1-oxo-7-phenylheptyl)amino]-4-(phenylmethoxy)-, (γS)-
MFCD06411576
sPLA2 inhibitor
(4S)-5-[4-(Benzyloxy)phenyl]-4-[(7-phenylheptanoyl)amino]pentanoic acid
5-(4-Benzyloxyphenyl)-4S-(7-phenylheptanoylamino)pentanoic acid
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
720.9±60.0 °C at 760 mmHg
[ Molecular Formula ]:
C31H37NO4
[ Molecular Weight ]:
487.63
[ Flash Point ]:
389.8±32.9 °C
[ Exact Mass ]:
487.272247
[ LogP ]:
6.16
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.573
[ Storage condition ]:
2-8°C
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
Articles
Curr. Med. Chem. 12(25) , 3011-26, (2005)
Phospholipases A2 cleave membrane phospholipids to release arachidonic acid, the precursor to a large family of pro-inflammatory eicosanoids including prostaglandins and leukotrienes that have been pr...
J. Immunol. 176(11) , 7000-7, (2006)
The development of fibrosis in the chronically hypertensive heart is associated with infiltration of inflammatory cells and cardiac hypertrophy. In this study, an inhibitor of the proinflammatory enzy...
J. Thorac. Cardiovasc. Surg. 144(6) , 1479-85, (2012)
There are currently no targeted therapies against lung tumors with oncogenic K-ras mutations that are found in 25% to -40% of lung cancers and are characterized by their resistance to epidermal growth...