1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinoline iodide

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Names

[ CAS No. ]:
3947-79-3

[ Name ]:
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinoline iodide

[Synonym ]:
1-acetoxy-2-methyl-3,4-dihydronaphthalene
1-acetoxy-2-methyltetral-1-ene
2-methyl-3,4-dihydropapaverinium iodide
6,7-Dimethoxy-2-methyl-1-veratryl-3,4-dihydro-isochinolinium,Jodid
6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-isoquinolinium,iodide
3,4-dihydro-2-methylnaphthal-1-enyl acetate
1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium iodide
1-Naphthalenol,3,4-dihydro-2-methyl-,acetate
3,4-dihydro-2-methyl-naphthalen-1-yl acetate
2-methyl-3,4-dihydronaphthalen-1-yl acetate

Chemical & Physical Properties

[ Molecular Formula ]:
C21H26INO4

[ Molecular Weight ]:
483.34000

[ Exact Mass ]:
483.09100

[ PSA ]:
39.93000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5138000
CHEMICAL NAME :
Isoquinolinium, 3,4-dihydro-6,7-dimethoxy-2-methyl-1-veratryl-, iodide
CAS REGISTRY NUMBER :
3947-79-3
LAST UPDATED :
198502
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H26-N-O4.I
MOLECULAR WEIGHT :
483.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
185 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 88,1197,1968

Synthetic Route

Precursor & DownStream

Precursor

  • 1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline
  • methyl iodide

DownStream

  • 1(2H)-Isoquinolinone,3,4-dihydro-6,7-dimethoxy-2-methyl-
  • 1-Oxo-2-methyl-6,7-dimethoxy-1,2-dihydroisoquinoline
  • Methanone,(6,7-dimethoxy-1-isoquinolinyl)(3,4-dimethoxyphenyl)-
  • 2-(2-(benzyloxy)-3,4-dimethoxyphenyl)oxirane

Related Compounds

  • 3-Morpholinone, 2,2-difluoro-4-phenyl-
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanoyl]-3-methylpyrrolidine-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 3-(((2-Formylphenyl)amino)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Methyl tetrahydro-2-(2-methylphenyl)-5-oxo-2-furanacetate