4-(Trifluoromethyl)Mandelic Acid

Names

[ CAS No. ]:
395-35-7

[ Name ]:
4-(Trifluoromethyl)Mandelic Acid

[Synonym ]:
EINECS 206-900-1
MFCD00009724
2-hydroxy-2-[4-(trifluoromethyl)phenyl]acetic acid
2-Hydroxy-2-(4-(trifluoromethyl)phenyl)acetic acid

Chemical & Physical Properties

[ Density]:
1.481 g/cm3

[ Boiling Point ]:
324.2ºC at 760 mmHg

[ Melting Point ]:
130-134 °C

[ Molecular Formula ]:
C₉H₇F₃O₃

[ Molecular Weight ]:
220.14500

[ Flash Point ]:
149.8ºC

[ Exact Mass ]:
220.03500

[ PSA ]:
57.53000

[ LogP ]:
1.82340

[ Index of Refraction ]:
1.502

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

DownStream

4-(Trifluoromethyl)benzaldehyde
4-(Trifluoromethyl)benzoic acid
4-(Trifluoromethyl)benzamide

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Bioanalysis of p-trifluoromethylmandelic acid and Mosher's acid by chiral gas chromatography and fluorine nuclear magnetic resonance to study chiral inversion: application to rat urine samples.

J. Chromatogr. B. Biomed. Sci. Appl. 695(2) , 279-85, (1997)

Methods for the nuclear magnetic resonance and gas chromatographic analysis of the enantiomers of p-trifluoromethylmandelic acid (p-TFM) and Mosher's acid (alpha-methoxy-alpha-(trifluoromethyl)phenyla...

Bi0-Catalyzed Oxidation of Mandelic Acid Derivatives: Substrate Selectivity. Favier I, et al.

European J. Org. Chem. 2002(12) , 1984-88, (2002)

4-(TRIFLUOROMETHYL)MANDELIC ACID
L-Cystine,N,N'-diformyl-
2-trifluoromethyl-4-fluoromandelic acid
3,5-BIS(TRIFLUOROMETHYL)MANDELIC ACID
4-(trifluoromethyl)benzoic acid butyl ester
4-(Trifluoromethyl)cyclohexanecarboxylic acid
((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-(2-quinoxalin-6-yl-ethyl)-amine
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
2-(2,4-dichlorophenoxy)-N-((3-(thiophen-3-yl)pyrazin-2-yl)methyl)acetamide
3-[4-chloro-3-(trifluoromethyl)phenyl]tetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-imine 5,5-dioxide
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde