(±)-Befunolol

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Names

[ CAS No. ]:
39552-01-7

[ Name ]:
(±)-Befunolol

[Synonym ]:
Befunolol HCl
(±)-Befunolol

Chemical & Physical Properties

[ Density]:
1.1049 (rough estimate)

[ Boiling Point ]:
433.35°C (rough estimate)

[ Melting Point ]:
115°

[ Molecular Formula ]:
C₁₆H₂₁NO₄

[ Molecular Weight ]:
291.34200

[ Exact Mass ]:
291.14700

[ PSA ]:
71.70000

[ LogP ]:
2.76400

[ Index of Refraction ]:
1.5500 (estimate)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OB4310000

CHEMICAL NAME :: Ketone, 7-(2-hydroxy-3-(isopropylamino)propoxy)-2-benzofurany l methyl

CAS REGISTRY NUMBER :: 39552-01-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H21-N-O4

MOLECULAR WEIGHT :: 291.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2223184

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-isopropyl-5-(2-acetyl-7-benzofuranoxymethyl)oxazolidone
2-acetyl-7-(2-hydroxy-3-aminopropoxy)benzofuran
2-Bromopropane
2-phenyl-3-isopropyl-5-(2-acetyl-7-benzofuranoxymethyl)oxazolidine
2-acetyl-7-[2-hydroxy-3-(N-acetyl-N-isopropyl)aminopropoxy]benzofuran
2-acetyl-7-hydroxybenzo[b]furan potassium salt
isopropylamine
Epichlorohydrin
2-(hydroxyethyl)-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran
2-acetyl-7-glycidyloxybenzo[b]furan

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%