Azatadine

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Names

[ CAS No. ]:
3964-81-6

[ Name ]:
Azatadine

[Synonym ]:
11-(1-methyl-piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2Z)-but-2-enedioate (1:2)
Azatadinum [INN-Latin]
Azatadina [INN-Spanish]
11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,4-b]pyridine
Azatadina
Optimine
Azatadinum
Azatidine
5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-, (2Z)-2-butenedioate (1:2)
11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2Z)-2-butenedioate (1:2)
Azatadine [INN:BAN]
6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
6,11--dihydro-11-(N-methyl-4-piperidylidene)-5H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridine
Azatadine maleate
Zadine
AZATADINE

Chemical & Physical Properties

[ Density]:
1.127 g/cm3

[ Boiling Point ]:
450.1ºC at 760 mmHg

[ Melting Point ]:
124-126ºC

[ Molecular Formula ]:
C20H22N2

[ Molecular Weight ]:
290.40

[ Flash Point ]:
226ºC

[ PSA ]:
16.13000

[ LogP ]:
3.64560

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
  • N-tert-butyl-3-methylpyridine-2-carboxamide
  • Benzyl chloride
  • 3-phenethyl-pyridine-2-carbonitrile
  • magnesium,1-methylpiperidin-4-ide,chloride
  • 6-11-dihydro-11-(1-methylpiperidin-4-yl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • AZATADINE
  • 9-chloro azatadine
  • Azatadine maleate mixture with pseudoephedrine sulfate
  • 1-[3-cyclopropyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]piperidine-4-carboxylic acid
  • (2S)-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbut-2-enoyl]-4,4-difluoropyrrolidine-2-carboxylic acid
  • 2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]-2-methylpropanoic acid
  • 1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutaneamido]cyclobutane-1-carboxylic acid
  • 6-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]hexanoic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoyl]-3-propylpyrrolidine-3-carboxylic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexanecarbonyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{methyl[(3-methyl-1,4-dioxan-2-yl)methyl]carbamoyl}propanoic acid
  • 2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
  • 5-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]cyclohex-3-ene-1-carboxylic acid
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