3,4-o-isopropylidene-d-mannitol

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Names

[ CAS No. ]:
3969-84-4

[ Name ]:
3,4-o-isopropylidene-d-mannitol

[Synonym ]:
3,4-Isopropylidene-D-mannitol
(1R)-1-[(4R,5R)-5-[(1R)-1,2-dihydroxyethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol
MFCD00075122
3,4-O-Isopropylidene-D-Mannitol
(1R,1'R)-1,1'-((4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(ethane-1,2-diol)

Chemical & Physical Properties

[ Density]:
1.303 g/cm3

[ Boiling Point ]:
438.8ºC at 760 mmHg

[ Melting Point ]:
85-88 °C(lit.)

[ Molecular Formula ]:
C9H18O6

[ Molecular Weight ]:
222.24

[ Flash Point ]:
219.2ºC

[ Exact Mass ]:
222.11000

[ PSA ]:
99.38000

[ Index of Refraction ]:
29 ° (C=3, H2O)

[ Storage condition ]:
Store at 0°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • D-Mannitol
  • Acetone
  • (4R,4'R,4''R,5'R)-2,2,2',2',2'',2''-Hexamethyl-4,4':5',4''-ter(1,3-dioxolane)
  • [2-[5-(2-benzoyloxy-1-hydroxy-ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-hydroxy-ethyl] benzoate
  • acetic acid
  • Water

DownStream

  • (+)-1,4-di-o-tosyl-2,3-o-isopropylidene-d-threitol
  • Aliskiren
  • l-2,3-O-isopropylidenethreitol
  • benzyl N-[(2S)-1-[[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-1,6-diphenylhexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
  • 3-[(4R,5R)-5-(3-hydroxypropyl)-2,2-dimethyl-1,3-dioxolan-4-yl]propan-1-ol
  • (S)-2,3-Bis(benzyloxy)propan-1-ol

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 1,6-dideoxy-3,4-O-isopropylidene-D-mannitol
  • 1,2:5,6-dianhydro-3,4-O-isopropylidene-D-mannitol
  • 1,2,5,6-tetra-O-benzyl-3,4-O-isopropylidene-D-mannitol
  • 3,4-O-ISOPROPYLIDENE-D-ARABINOPYRANOSE
  • (1S)-1-allyl-2-[(9-phenylfluoren-9-yl)-amino]-2-deoxy-3,4,5,6-di-O-isopropylidene-D-mannitol
  • 4,5-bis(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-1,3-dioxolane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-butyl N-[3-amino-2-(5-bromothiophen-2-yl)-2-methylpropyl]carbamate
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide