1-(Chloromethoxy)-2-methoxyethane

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Names

[ CAS No. ]:
3970-21-6

[ Name ]:
1-(Chloromethoxy)-2-methoxyethane

[Synonym ]:
1-Chloromethoxy-2-methoxyethane
2-MethoxyethoxyMethyl Chloride
MFCD00000888
Ethylene Glycol Chloromethyl Methyl Ether
Ethane, 1-(chloromethoxy)-2-methoxy-
MEM chloride
1-(Chloromethoxy)-2-methoxyethane
EINECS 223-589-8
MEM-Chloride
β-Methoxyethoxymethyl chloride

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
161.3±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C4H9ClO2

[ Molecular Weight ]:
124.566

[ Flash Point ]:
32.4±15.6 °C

[ Exact Mass ]:
124.029106

[ PSA ]:
18.46000

[ LogP ]:
-0.07

[ Vapour Pressure ]:
3.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.402

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302-H315-H319-H335-H350

[ Precautionary Statements ]:
P201-P210-P280-P304 + P340 + P312-P308 + P313-P337 + P313

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R10;R36/37/38;R45

[ Safety Phrases ]:
S53-S26-S36/37/39-S45-S16

[ RIDADR ]:
UN 2810 6.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

Precursor & DownStream

Precursor

  • Thionyl chloride
  • BIS(2-METHOXYETHOXY)METHANE
  • Formaldehyde
  • 2-methoxyethanol
  • trioxane

DownStream

  • 4-(2-methoxyethoxymethoxy)benzonitrile
  • methyl 8-(2-methoxyethoxymethoxy)octanoate
  • BIS(2-METHOXYETHOXY)METHANE
  • BIS(CHLOROMETHYL) ETHER
  • Chloromethane
  • dimethyl ether
  • Chloromethyl methyl ether
  • dichloroethane
  • Bis(chloroethyl) ether
  • 10-(2-methoxyethoxymethyl)acridin-9-one

Articles

Protection of uracil residue with methoxyethoxymethyl group.

Nucleic Acids Symp. Ser. (12) , 51-4, (1983)

Synthesis of oligoribonucleotides using the methoxyethoxymethyl group as the protecting groups of the base residues and the hydroxyl functions.

Nucleic Acids Symp. Ser. (15) , 89-92, (1984)

Greene, T.W. Wuts, P.G.M.

Protective Groups in Organic Synthesis 3rd ed., New York , (1991)


More Articles


Related Compounds

  • 1-[(Chloromethoxy)methoxy]-2-methoxyethane
  • 1-chloromethoxy-2-propene
  • 1-(chloromethoxy)-2-[2-(chloromethoxy)phenyl]benzene
  • 1-(chloromethoxy)-2-dichlorophosphoryl-3-methylbut-1-ene
  • 1-(chloromethoxy)-2,2-dimethylpropane
  • 1-(chloromethoxy)-2-methylpropane
  • 1-(4-Fluoro-3-methoxyphenyl)cyclobutane-1-carbonitrile
  • 4-Methoxy-4-[(2-methoxy-1,3-thiazol-5-yl)methyl]piperidine
  • 2-Methoxy-3-(thian-3-yl)propanoic acid
  • ethyl 4-[(1S)-3-amino-1-hydroxypropyl]piperidine-1-carboxylate
  • methyl 2-hydroxy-2-{1-[2-(1H-1,2,3,4-tetrazol-1-yl)ethyl]cyclopropyl}acetate
  • 2-(1-Isocyanatocyclopropyl)-4,5,6,7-tetrahydro-1-benzothiophene
  • 2-(2,4-Dimethoxypyridin-3-yl)ethanethioamide
  • Methyl 4-(1-amino-2,2-dimethylcyclopropyl)-2-methylbenzoate
  • 1-{[4-(Methoxycarbonyl)-5-methylfuran-2-yl]methyl}cyclopropane-1-carboxylic acid
  • rac-(1R,2R)-2-{5H,6H,7H,8H-imidazo[1,2-a]pyridin-2-yl}cyclopropane-1-carboxylic acid