5-PHENYL-O-ANISIDINE

Names

[ Name ]:
5-PHENYL-O-ANISIDINE

[Synonym ]:
2-Amino-4-phenylanisole
3-Amino-4-methoxybiphenyl
4-Methoxy-[1,1'-biphenyl]-3-amine
5-Phenyl-o-anisidine
EINECS 254-639-7
2-methoxy-5-phenylaniline
MFCD00007790

Chemical & Physical Properties

[ Density]:
1.042g/cm3

[ Boiling Point ]:
337.8ºC at 760 mmHg

[ Melting Point ]:
82-83 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₃NO

[ Molecular Weight ]:
199.24800

[ Flash Point ]:
159ºC

[ Exact Mass ]:
199.10000

[ PSA ]:
35.25000

[ LogP ]:
3.52560

[ Index of Refraction ]:
1.553

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Methoxy-3-nitrobiphenyl
3-(4-methoxy-[1,1'-biphenyl]-3-yl)-1-((phenylthio)methyl)triaz-1-ene
5-Phenylazobenzene-2-ol
4-Biphenylol
2-chloro-1-methoxy-4-phenylbenzene
3-Nitro-4-biphenylol
4-BROMO-3-NITROBIPHENYL
Ammonia

DownStream

Articles

X-ray Diffraction and DFT Studies of 2-Methoxy-5-phenylaniline. Marques AT, et al.

J. Chem. Crystallogr. 38(4) , 295-99, (2008)

Synthesis and biological evaluation of nonclassical 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines with novel side chain substituents as potential inhibitors of dihydrofolate reductases.

J. Med. Chem. 40(4) , 479-85, (1997)

Nine novel 2,4-diamino-5-methyl-6-substituted-pyrido[2,3-d]pyrimidines, 2-10, were synthesized as potential inhibitors of Pneumocystis carinii dihydrofolate reductase (pcDHFR) and Toxoplasma gondii di...