5-Fluoroindole-2-carboxylic acid
Suppliers
Names
[ CAS No. ]:
399-76-8
[ Name ]:
5-Fluoroindole-2-carboxylic acid
[Synonym ]:
5-Fluoro-1H-indole-2-carboxylic acid
5-Fluoroindole-2-carboxylic acid
1H-Indole-2-carboxylic acid, 5-fluoro-
MFCD00005612
EINECS 206-919-5
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
422.2±25.0 °C at 760 mmHg
[ Melting Point ]:
259 °C (dec.)(lit.)
[ Molecular Formula ]:
C9H6FNO2
[ Molecular Weight ]:
179.148
[ Flash Point ]:
209.1±23.2 °C
[ Exact Mass ]:
179.038254
[ PSA ]:
53.09000
[ LogP ]:
2.45
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.692
[ Storage condition ]:
0-6°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatme...
Chem. Biol. 13(3) , 261-8, (2006)
Severe acute respiratory syndrome (SARS) is caused by a newly emerged coronavirus that infected more than 8000 individuals and resulted in more than 800 fatalities in 2003. Currently, there is no effe...
J. Neural Transm. Gen. Sect. 105(2-3) , 133-46, (1998)
5-Fluoroindole-2-carboxylic acid, an antagonist of the glycine site within the NMDA receptor complex, administered intraperitoneally in doses of 150 and 200 mg/kg, 120 min before electroconvulsions, s...