2-[2-cyclopentylimino-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid

Names

[ CAS No. ]:
39964-47-1

[ Name ]:
2-[2-cyclopentylimino-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid

[Synonym ]:
2-(Cyclopentylimino)-4-oxo-3-(p-tolyl)-5-thiazolidineacetic acid
[(2z)-2-(cyclopentylimino)-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid
(2-cyclopentylimino-4-oxo-3-p-tolyl-thiazolidin-5-yl)-acetic acid
5-Thiazolidineacetic acid,2-(cyclopentylimino)-4-oxo-3-(p-tolyl)

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
536.4ºC at 760 mmHg

[ Molecular Formula ]:
C17H20N2O3S

[ Molecular Weight ]:
332.41700

[ Flash Point ]:
278.2ºC

[ Exact Mass ]:
332.11900

[ PSA ]:
95.27000

[ LogP ]:
3.28170

[ Index of Refraction ]:
1.671

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ5131589
CHEMICAL NAME :
5-Thiazolidineacetic acid, 2-(cyclopentylimino)-4-oxo-3-(p-tolyl)-
CAS REGISTRY NUMBER :
39964-47-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H20-N2-O3-S
MOLECULAR WEIGHT :
332.45
WISWESSER LINE NOTATION :
T5SYNV EHJ CR D1& E1VQ BUN- AL5TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,178,1973

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Maleic anhydride

DownStream

Related Compounds

  • N-[(4-Methylphenyl)methyl]-N-prop-2-ynylprop-2-enamide
  • tert-Butyl 5-cyano-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate
  • N-(2-Chloro-6-methylphenyl)-N-methylacetamide
  • 1,3-Dioxoisoindolin-2-yl 1-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoate
  • 1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl 2-(3-chlorophenoxy)propanoate
  • 1,3-Dioxoisoindolin-2-yl 2,3-dihydrobenzo[b][1,4]dioxine-2-carboxylate
  • 4-tert-butyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) morpholine-3,4-dicarboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-{[(tert-butoxy)carbonyl]amino}-4-(methylsulfanyl)butanoate
  • N-boc-3-(methylamino)-1-(2-thienyl)-1-propanone