2-[2-cyclopentylimino-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid

Names

[ CAS No. ]:
39964-47-1

[ Name ]:
2-[2-cyclopentylimino-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid

[Synonym ]:
2-(Cyclopentylimino)-4-oxo-3-(p-tolyl)-5-thiazolidineacetic acid
[(2z)-2-(cyclopentylimino)-3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-5-yl]acetic acid
(2-cyclopentylimino-4-oxo-3-p-tolyl-thiazolidin-5-yl)-acetic acid
5-Thiazolidineacetic acid,2-(cyclopentylimino)-4-oxo-3-(p-tolyl)

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
536.4ºC at 760 mmHg

[ Molecular Formula ]:
C17H20N2O3S

[ Molecular Weight ]:
332.41700

[ Flash Point ]:
278.2ºC

[ Exact Mass ]:
332.11900

[ PSA ]:
95.27000

[ LogP ]:
3.28170

[ Index of Refraction ]:
1.671

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ5131589
CHEMICAL NAME :
5-Thiazolidineacetic acid, 2-(cyclopentylimino)-4-oxo-3-(p-tolyl)-
CAS REGISTRY NUMBER :
39964-47-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H20-N2-O3-S
MOLECULAR WEIGHT :
332.45
WISWESSER LINE NOTATION :
T5SYNV EHJ CR D1& E1VQ BUN- AL5TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,178,1973

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Maleic anhydride

DownStream

Related Compounds

  • 4-(4-Methyl-6-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyrimidin-2-yl)morpholine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Chloro-N-pyrazolo[1,5-a]pyridin-7-ylacetamide
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-(4-Chlorophenyl)-4H-1,3-benzothiazine-4-thione
  • 2-(4-(ethylsulfonyl)phenyl)-N-(4-methoxy-2-nitrophenyl)acetamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide