Trimethylsilyl trifluoroacetate

Suppliers

Names

[ CAS No. ]:
400-53-3

[ Name ]:
Trimethylsilyl trifluoroacetate

[Synonym ]:
MFCD00000413
Acetic acid, 2,2,2-trifluoro-, trimethylsilyl ester
Trifluoroacetic Acid Trimethylsilyl Ester
trimethylsilyl 2,2,2-trifluoroacetate
Acetic acid, trifluoro-, trimethylsilyl ester
EINECS 206-923-7
Trimethylsilyl trifluoroacetate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
89.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C5H9F3O2Si

[ Molecular Weight ]:
186.204

[ Flash Point ]:
-0.6±0.0 °C

[ Exact Mass ]:
186.032394

[ PSA ]:
26.30000

[ LogP ]:
2.76

[ Vapour density ]:
>1 (vs air)

[ Vapour Pressure ]:
59.7±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.353

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;C: Corrosive;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S26-S36/37/39-S45

[ RIDADR ]:
UN 2924 3/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3.1

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Bis(trimethylsilyl) sulfate
  • Sodium perfluoroacetate
  • Trifluoroacetyl chloride
  • POTASSIUM TRIMETHYLSILANOLATE
  • diisopropyl(carboethoxyfluoromethyl)phosphonate
  • Chlorotrimethylsilane
  • trifluoroacetic acid
  • 1-(Trimethylsilyl)piperidine-2-one
  • Dimethylchloromethyltrifluoroacetoxysilane

DownStream

  • BUTOXYTRIMETHYLSILANE
  • Hexamethyldisiloxane
  • Acetic acid,2,2,2-trifluoro-, butyl ester
  • Ethyl trifluoroacetoacetate
  • Fluoro(trimethyl)silane
  • boron tris(trifluoroacetate)
  • PHENYL TRIFLUOROACETATE
  • Tetrakis(trimethylsilyl) orthosilicate
  • 7,7-difluorobicyclo[4.1.0]heptane
  • Tetrafluoroethylene

Articles

M. Demuth et al.

Helv. Chim. Acta 64 , 2759, (1981)

Y. Tanabe et al.

J. Org. Chem. 53 , 4582, (1988)


More Articles

Related Compounds

  • trimethylsilyl trifluoroacetate phenylhydrazone
  • (Trimethylsilyl)(p-tert-butylphenyl)-methanol
  • trimethylsilyl 4,4,4-trifluoro-3-(trimethylsilylamino)butanoate
  • (trimethylsilyl)sodium
  • Trimethylsilyl-10-undecenoate
  • Trimethylsilyl O,O'-bis(trimethylsilyl)vanilmandelate
  • methyl 3-hydroxy-3-(1H-indazol-7-yl)propanoate
  • [1-(1H-indazol-7-yl)cyclopropyl]methanol
  • (2R)-1-[2-(propan-2-yloxy)phenyl]propan-2-amine
  • (2S)-1-(1,4-dimethyl-1H-pyrazol-3-yl)propan-2-ol
  • (1R)-3-amino-1-[1-methyl-3-(oxan-4-yl)-1H-pyrazol-4-yl]propan-1-ol
  • 2-(2-Cyclopropyl-1,3-thiazol-4-yl)prop-2-enoic acid
  • 4-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-5-oxopyrrolidine-3-carboxylic acid
  • Tert-butyl 2-amino-4-bromo-5-fluorobenzoate
  • 5-Formyl-2-methoxythiophene-3-carboxylic acid
  • 2-[(Hex-5-yn-1-yl)amino]-1,3-thiazole-4-carboxylic acid