2-[4-(2-methylphenyl)piperazin-1-yl]ethanol

Names

[ CAS No. ]:
40004-66-8

[ Name ]:
2-[4-(2-methylphenyl)piperazin-1-yl]ethanol

[Synonym ]:
1-Piperazineethanol,4-o-tolyl
4-o-Tolyl-1-piperazineethanol

Chemical & Physical Properties

[ Density]:
1.079g/cm3

[ Boiling Point ]:
366.2ºC at 760 mmHg

[ Molecular Formula ]:
C13H20N2O

[ Molecular Weight ]:
220.31100

[ Flash Point ]:
182.4ºC

[ Exact Mass ]:
220.15800

[ PSA ]:
26.71000

[ LogP ]:
1.11220

[ Index of Refraction ]:
1.557

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL9610000
CHEMICAL NAME :
1-Piperazineethanol, 4-o-tolyl-
CAS REGISTRY NUMBER :
40004-66-8
BEILSTEIN REFERENCE NO. :
0199355
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H20-N2-O
MOLECULAR WEIGHT :
220.35
WISWESSER LINE NOTATION :
T6N DNTJ A2Q DR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#08359

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • o-Toluidine HCl
  • ETHYLENE OXIDE
  • 1-(2-Methylphenyl)piperazine

DownStream

  • trimethyl-[2-[4-(2-methylphenyl)piperazin-1-yl]ethoxy]silane
  • 2-[4-(2-methylphenyl)piperazin-1-yl]ethyl 3-oxobutanoate

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-[4-(2-methylphenyl)piperazin-1-yl]-1-thiophen-2-ylethanol,hydrochloride
  • 2-[4-(2-methylphenyl)piperazin-1-yl]-1-pyridin-3-ylethanol
  • 2-[4-(2-methylphenyl)piperazin-1-yl]ethyl 3-oxobutanoate
  • 2-[2-(methoxymethyl)-4-(2-methylphenyl)piperazin-1-yl]ethanol
  • 4-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]benzene-1,2-diol,hydrate,dihydrobromide
  • trimethyl-[2-[4-(2-methylphenyl)piperazin-1-yl]ethoxy]silane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(3-{[3-(3-cyanophenoxy)-2-(3-methoxyphenyl)-4-oxoazetidin-1-yl]methyl}phenyl)cyclopropanecarboxamide
  • 1H-Benzimidazole, 2-(2-chloroethyl)-1-(3-fluorophenyl)-
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine