(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoic acid

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Names

[ CAS No. ]:
402958-96-7

[ Name ]:
(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoic acid

[Synonym ]:
val002
L-Valine, N-[(2S)-2-cyclohexyl-2-[(2-pyrazinylcarbonyl)amino]acetyl]-3-methyl-
N-{(2S)-2-Cyclohexyl-2-[(2-pyrazinylcarbonyl)amino]acetyl}-3-methyl-L-valine
(S)-2-((S)-2-CYCLOHEXYL-2-[(PYRAZINE-2-CARBONYL)-AMINO]-ACETYLAMINO)-3,3-DIMETHYL-BUTYRIC ACID

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
677.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H28N4O4

[ Molecular Weight ]:
376.450

[ Flash Point ]:
363.6±31.5 °C

[ Exact Mass ]:
376.211060

[ PSA ]:
121.28000

[ LogP ]:
2.52

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-Methyl 2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate
  • Boc-Chg-OH
  • Pyrazine-2-carboxylic acid
  • H-Tle-OMe.HCl
  • methyl (2S)-2-amino-2-cyclohexylacetate
  • (S)-2-Cyclohexyl-2-(Pyrazine-2-Carboxamido)Acetic Acid
  • Cyclohexaneacetic acid, α-[(2-pyrazinylcarbonyl)amino]-, Methyl ester, (αS)-
  • L-Cyclohexylglycine

DownStream

  • Des[N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]carboxamido] 1-Carboxy Telaprevir
  • Telaprevir (VX-950)

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%